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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
22.42
Human Site:
Y683
Identified Species:
32.89
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
Y683
L
K
M
S
G
L
R
Y
N
E
W
L
Q
D
G
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
Y775
L
K
M
S
G
L
R
Y
N
E
W
L
Q
D
G
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
Y935
L
K
M
S
G
L
R
Y
N
E
W
L
Q
D
G
Dog
Lupus familis
XP_547953
806
90703
Y690
L
K
M
S
G
L
R
Y
N
E
W
L
Q
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
P659
R
G
L
L
T
V
D
P
A
K
R
L
K
L
E
Rat
Rattus norvegicus
Q63531
735
82865
P613
T
M
L
A
G
Y
T
P
F
A
N
G
P
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
Y600
L
K
M
S
G
L
R
Y
N
E
W
L
Q
D
G
Chicken
Gallus gallus
Q5F3L1
789
89022
Y673
I
K
M
S
S
L
R
Y
N
E
W
L
Q
D
G
Frog
Xenopus laevis
P10665
733
82620
D618
P
F
A
N
G
L
G
D
T
P
E
E
I
L
A
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
R630
T
P
E
E
I
L
L
R
I
G
S
G
K
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
D882
P
T
L
S
D
I
L
D
S
E
W
L
Q
Y
G
Honey Bee
Apis mellifera
XP_395099
910
102507
N702
H
P
W
L
Q
E
S
N
S
F
D
V
A
S
S
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
A649
L
S
M
Q
E
L
T
A
H
M
W
L
K
S
S
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
Q643
L
T
T
D
D
L
L
Q
N
E
W
I
Q
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
E362
L
P
Q
F
L
S
N
E
A
H
A
L
L
K
G
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
A568
F
P
D
G
F
D
P
A
A
K
D
L
L
I
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
100
86.6
13.3
6.6
N.A.
40
0
33.3
40
P-Site Similarity:
100
100
100
100
N.A.
33.3
20
N.A.
100
93.3
20
13.3
N.A.
60
13.3
46.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
0
0
13
19
7
7
0
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
7
13
7
7
13
0
0
13
0
0
38
7
% D
% Glu:
0
0
7
7
7
7
0
7
0
50
7
7
0
0
7
% E
% Phe:
7
7
0
7
7
0
0
0
7
7
0
0
0
7
0
% F
% Gly:
0
7
0
7
44
0
7
0
0
7
0
13
0
7
57
% G
% His:
7
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% H
% Ile:
7
0
0
0
7
7
0
0
7
0
0
7
7
7
0
% I
% Lys:
0
38
0
0
0
0
0
0
0
13
0
0
19
7
0
% K
% Leu:
50
0
19
13
7
63
19
0
0
0
0
69
13
13
0
% L
% Met:
0
7
44
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
7
7
44
0
7
0
0
0
0
% N
% Pro:
13
25
0
0
0
0
7
13
0
7
0
0
7
0
0
% P
% Gln:
0
0
7
7
7
0
0
7
0
0
0
0
50
0
7
% Q
% Arg:
7
0
0
0
0
0
38
7
0
0
7
0
0
0
0
% R
% Ser:
0
7
0
44
7
7
7
0
13
0
7
0
0
19
19
% S
% Thr:
13
13
7
0
7
0
13
0
7
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
57
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
38
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _