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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
24.24
Human Site:
Y78
Identified Species:
35.56
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
Y78
G
H
D
T
G
K
L
Y
A
M
K
V
L
K
K
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
Y170
G
H
D
T
G
K
L
Y
A
M
K
V
L
K
K
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
Y336
G
H
D
T
G
K
L
Y
A
M
K
V
L
K
K
Dog
Lupus familis
XP_547953
806
90703
Y85
G
H
D
A
G
K
L
Y
A
M
K
V
L
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
E85
T
Q
E
H
T
R
T
E
R
S
V
L
E
L
V
Rat
Rattus norvegicus
Q63531
735
82865
G88
K
V
T
R
P
D
N
G
H
L
Y
A
M
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
Y74
T
E
N
E
V
Q
I
Y
I
G
E
I
V
L
A
Chicken
Gallus gallus
Q5F3L1
789
89022
Q93
E
H
T
R
T
E
R
Q
V
L
E
H
I
R
Q
Frog
Xenopus laevis
P10665
733
82620
N88
K
I
T
P
P
D
A
N
Q
L
Y
A
M
K
V
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
G93
K
L
M
G
P
D
A
G
Q
L
Y
A
M
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
Y290
R
H
D
A
G
K
L
Y
A
M
K
V
L
N
K
Honey Bee
Apis mellifera
XP_395099
910
102507
Y93
G
T
D
A
G
R
L
Y
A
M
K
V
L
K
K
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
F81
E
R
L
R
G
T
P
F
L
V
N
L
F
Y
A
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
Y79
P
F
L
V
T
L
H
Y
A
F
Q
T
D
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
R59
H
E
H
E
H
H
I
R
K
I
N
T
N
E
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
93.3
N.A.
0
6.6
N.A.
6.6
6.6
6.6
6.6
N.A.
80
80
6.6
20
P-Site Similarity:
100
100
100
93.3
N.A.
20
20
N.A.
46.6
46.6
20
20
N.A.
80
86.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
0
13
0
44
0
0
19
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
38
0
0
19
0
0
0
0
0
0
7
0
0
% D
% Glu:
13
13
7
13
0
7
0
7
0
0
13
0
7
7
0
% E
% Phe:
0
7
0
0
0
0
0
7
0
7
0
0
7
0
0
% F
% Gly:
32
0
0
7
44
0
0
13
0
7
0
0
0
0
0
% G
% His:
7
38
7
7
7
7
7
0
7
0
0
7
0
0
0
% H
% Ile:
0
7
0
0
0
0
13
0
7
7
0
7
7
0
0
% I
% Lys:
19
0
0
0
0
32
0
0
7
0
38
0
0
50
44
% K
% Leu:
0
7
13
0
0
7
38
0
7
25
0
13
38
13
0
% L
% Met:
0
0
7
0
0
0
0
0
0
38
0
0
19
0
0
% M
% Asn:
0
0
7
0
0
0
7
7
0
0
13
0
7
7
0
% N
% Pro:
7
0
0
7
19
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
7
0
7
13
0
7
0
0
0
7
% Q
% Arg:
7
7
0
19
0
13
7
7
7
0
0
0
0
7
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% S
% Thr:
13
7
19
19
19
7
7
0
0
0
0
13
0
0
7
% T
% Val:
0
7
0
7
7
0
0
0
7
7
7
38
7
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
19
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _