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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GCAT All Species: 45.45
Human Site: Y292 Identified Species: 90.91
UniProt: O75600 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75600 NP_055106.1 419 45285 Y292 L R Q R A R P Y L F S N S L P
Chimpanzee Pan troglodytes XP_515122 419 45302 Y292 L R Q R A R P Y L F S N S L P
Rhesus Macaque Macaca mulatta XP_001089366 419 45019 Y292 L R Q R A R P Y L F S N S L P
Dog Lupus familis XP_538383 419 45083 Y292 L R Q R A R P Y L F S N S L P
Cat Felis silvestris
Mouse Mus musculus O88986 416 44912 Y289 L R Q R S R P Y L F S N S L P
Rat Rattus norvegicus NP_001019448 416 45205 Y289 M R Q R S R P Y L F S N S L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425478 419 45179 Y292 L R Q R S R P Y L F S N S L P
Frog Xenopus laevis NP_001080801 416 45277 Y289 L R Q R S R P Y L F S N T L P
Zebra Danio Brachydanio rerio NP_001166025 431 46435 Y304 L R Q R S R P Y L F S N S L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648509 417 45523 Y290 L R Q K S R P Y L F S N T L P
Honey Bee Apis mellifera XP_395385 407 45184 Y280 L K Q R S R P Y L F S N S L P
Nematode Worm Caenorhab. elegans NP_501991 420 45476 F294 Q R S R P Y L F S N S L A P S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 96.6 92.3 N.A. 90.9 90.6 N.A. N.A. 84.2 77.5 70.5 N.A. 64.6 59.1 59.2 N.A.
Protein Similarity: 100 99.7 97.6 94.5 N.A. 94.5 95.4 N.A. N.A. 90.4 88 82.5 N.A. 78 73.2 73.5 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 86.6 N.A. N.A. 93.3 86.6 93.3 N.A. 80 86.6 20 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 100 100 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 34 0 0 0 0 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 92 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 84 0 0 0 0 0 9 0 92 0 0 9 0 92 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 9 0 92 0 0 0 % N
% Pro: 0 0 0 0 9 0 92 0 0 0 0 0 0 9 92 % P
% Gln: 9 0 92 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 92 0 92 0 92 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 9 0 59 0 0 0 9 0 100 0 75 0 9 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 92 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _