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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCM2
All Species:
17.88
Human Site:
S286
Identified Species:
39.33
UniProt:
O75603
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75603
NP_004743.1
506
56610
S286
N
P
G
Y
T
N
S
S
P
Y
P
T
L
Y
K
Chimpanzee
Pan troglodytes
XP_518235
506
56544
S286
N
P
G
Y
T
N
S
S
P
Y
P
T
L
Y
K
Rhesus Macaque
Macaca mulatta
XP_001088392
506
56526
S286
N
P
G
Y
T
N
T
S
P
Y
P
T
L
Y
K
Dog
Lupus familis
XP_545339
678
74730
S458
A
P
R
Y
T
N
S
S
P
H
P
T
L
Y
K
Cat
Felis silvestris
Mouse
Mus musculus
O09102
504
56020
S286
S
S
G
V
T
G
S
S
P
Y
S
T
L
Y
K
Rat
Rattus norvegicus
Q9Z288
436
49504
S219
V
Q
L
P
S
G
Y
S
T
P
L
I
A
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514393
474
53557
M254
C
P
N
P
R
I
Y
M
P
R
P
P
C
G
Y
Chicken
Gallus gallus
NP_001008480
471
52775
I253
Q
K
C
P
N
P
R
I
Y
V
P
R
P
C
S
Frog
Xenopus laevis
NP_001089012
481
54743
S261
L
S
S
F
Q
K
C
S
N
A
R
I
Y
M
A
Zebra Danio
Brachydanio rerio
NP_001005603
496
55696
Y278
V
T
R
P
P
C
G
Y
D
F
A
V
P
G
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLA2
613
66648
L376
A
P
S
K
S
P
S
L
P
Y
A
C
S
I
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
95.6
61.5
N.A.
68.7
32.2
N.A.
59.2
51.3
51.1
48.8
N.A.
26.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
96.8
66.3
N.A.
78
46
N.A.
67.9
65.6
67
65.4
N.A.
38.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
66.6
6.6
N.A.
20
6.6
6.6
0
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
73.3
13.3
N.A.
20
6.6
13.3
6.6
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
0
0
0
0
0
0
10
19
0
10
0
19
% A
% Cys:
10
0
10
0
0
10
10
0
0
0
0
10
10
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
37
0
0
19
10
0
0
0
0
0
0
19
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
10
0
0
0
19
0
10
0
% I
% Lys:
0
10
0
10
0
10
0
0
0
0
0
0
0
0
46
% K
% Leu:
10
0
10
0
0
0
0
10
0
0
10
0
46
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% M
% Asn:
28
0
10
0
10
37
0
0
10
0
0
0
0
10
0
% N
% Pro:
0
55
0
37
10
19
0
0
64
10
55
10
19
0
0
% P
% Gln:
10
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
19
0
10
0
10
0
0
10
10
10
0
0
0
% R
% Ser:
10
19
19
0
19
0
46
64
0
0
10
0
10
0
19
% S
% Thr:
0
10
0
0
46
0
10
0
10
0
0
46
0
0
0
% T
% Val:
19
0
0
10
0
0
0
0
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
37
0
0
19
10
10
46
0
0
10
46
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _