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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GCM2 All Species: 13.03
Human Site: Y320 Identified Species: 28.67
UniProt: O75603 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75603 NP_004743.1 506 56610 Y320 N V N S Y S S Y E R S F D F T
Chimpanzee Pan troglodytes XP_518235 506 56544 Y320 N V N S Y S S Y E R S F D F T
Rhesus Macaque Macaca mulatta XP_001088392 506 56526 Y320 N V N S Y S S Y E R S F D F T
Dog Lupus familis XP_545339 678 74730 F492 N V N S Y G S F E R S F D F T
Cat Felis silvestris
Mouse Mus musculus O09102 504 56020 Y320 N V S S Y G S Y E R T L D F T
Rat Rattus norvegicus Q9Z288 436 49504 P253 G T T E L E D P T S T L D P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514393 474 53557 A288 A N S C F P D A D W V N W T G
Chicken Gallus gallus NP_001008480 471 52775 D287 D P A N P P L D A D P I S L N
Frog Xenopus laevis NP_001089012 481 54743 G295 T L Y K E P L G S L S D T D R
Zebra Danio Brachydanio rerio NP_001005603 496 55696 G312 E T E P N K S G S S L S G V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLA2 613 66648 Q410 V H G H T Q C Q A V A Y D S S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 95.6 61.5 N.A. 68.7 32.2 N.A. 59.2 51.3 51.1 48.8 N.A. 26.5 N.A. N.A. N.A.
Protein Similarity: 100 99.4 96.8 66.3 N.A. 78 46 N.A. 67.9 65.6 67 65.4 N.A. 38.8 N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 73.3 13.3 N.A. 0 0 6.6 6.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 20 N.A. 20 13.3 13.3 13.3 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 0 0 10 19 0 10 0 0 0 0 % A
% Cys: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 19 10 10 10 0 10 64 10 0 % D
% Glu: 10 0 10 10 10 10 0 0 46 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 10 0 0 0 37 0 46 0 % F
% Gly: 10 0 10 0 0 19 0 19 0 0 0 0 10 0 10 % G
% His: 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 10 0 19 0 0 10 10 19 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 46 10 37 10 10 0 0 0 0 0 0 10 0 0 10 % N
% Pro: 0 10 0 10 10 28 0 10 0 0 10 0 0 10 0 % P
% Gln: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 46 0 0 0 0 10 % R
% Ser: 0 0 19 46 0 28 55 0 19 19 46 10 10 10 19 % S
% Thr: 10 19 10 0 10 0 0 0 10 0 19 0 10 10 55 % T
% Val: 10 46 0 0 0 0 0 0 0 10 10 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % W
% Tyr: 0 0 10 0 46 0 0 37 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _