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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP2
All Species:
12.73
Human Site:
S142
Identified Species:
25.45
UniProt:
O75604
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75604
NP_004196.4
605
68072
S142
T
L
T
Q
K
L
D
S
Q
S
D
L
A
R
D
Chimpanzee
Pan troglodytes
XP_508813
605
67980
S142
T
L
T
Q
K
S
D
S
Q
S
D
L
A
R
D
Rhesus Macaque
Macaca mulatta
XP_001105333
605
68108
S142
T
L
T
Q
K
S
D
S
Q
S
D
L
A
R
D
Dog
Lupus familis
XP_849718
606
68141
S143
L
T
Q
R
R
S
N
S
Q
S
D
L
A
R
D
Cat
Felis silvestris
Mouse
Mus musculus
O88623
613
68827
D150
S
Q
S
D
L
A
R
D
F
S
S
L
R
T
S
Rat
Rattus norvegicus
B2GUX4
565
62681
R120
S
V
S
S
G
D
L
R
P
M
G
I
A
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514295
291
33623
Chicken
Gallus gallus
O57429
357
40913
Frog
Xenopus laevis
Q6DCJ1
523
60090
K78
K
H
I
H
E
H
A
K
N
K
R
H
N
L
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
A269
V
I
D
A
Y
F
A
A
C
V
N
R
D
A
R
Honey Bee
Apis mellifera
XP_392493
643
70321
T180
Y
I
P
N
I
R
Q
T
S
S
T
T
G
S
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32571
926
105173
K300
L
V
N
H
S
F
E
K
P
I
S
D
D
F
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.6
92.4
N.A.
88.9
38.5
N.A.
43.1
49.7
23.7
N.A.
N.A.
24.6
37.1
N.A.
N.A.
Protein Similarity:
100
99.5
98.1
94.3
N.A.
92.3
54
N.A.
46.2
54.2
38.6
N.A.
N.A.
38.7
54.9
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
53.3
N.A.
13.3
6.6
N.A.
0
0
0
N.A.
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
73.3
N.A.
26.6
33.3
N.A.
0
0
6.6
N.A.
N.A.
20
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
9
17
9
0
0
0
0
42
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
9
25
9
0
0
34
9
17
0
34
% D
% Glu:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
17
0
0
9
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
9
0
9
0
9
% G
% His:
0
9
0
17
0
9
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
17
9
0
9
0
0
0
0
9
0
9
0
0
0
% I
% Lys:
9
0
0
0
25
0
0
17
0
9
0
0
0
0
0
% K
% Leu:
17
25
0
0
9
9
9
0
0
0
0
42
0
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
9
9
0
0
9
0
9
0
9
0
9
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
17
0
0
0
0
0
0
% P
% Gln:
0
9
9
25
0
0
9
0
34
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
9
9
9
9
0
0
9
9
9
34
9
% R
% Ser:
17
0
17
9
9
25
0
34
9
50
17
0
0
9
9
% S
% Thr:
25
9
25
0
0
0
0
9
0
0
9
9
0
9
17
% T
% Val:
9
17
0
0
0
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _