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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP2 All Species: 24.55
Human Site: S442 Identified Species: 49.09
UniProt: O75604 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75604 NP_004196.4 605 68072 S442 F D P F W D L S L P I A K R G
Chimpanzee Pan troglodytes XP_508813 605 67980 S442 F D P F W D L S L P I A K R G
Rhesus Macaque Macaca mulatta XP_001105333 605 68108 S442 F D P F W D L S L P I A K R G
Dog Lupus familis XP_849718 606 68141 S443 F D P F W D L S L P I A K R G
Cat Felis silvestris
Mouse Mus musculus O88623 613 68827 S450 F D P F W D L S L P I A K R G
Rat Rattus norvegicus B2GUX4 565 62681 P405 C D L S L P I P K K G F A G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514295 291 33623 G131 R I G D L F V G Q M K S S L T
Chicken Gallus gallus O57429 357 40913 L195 D P F W D L S L P I P K K G Y
Frog Xenopus laevis Q6DCJ1 523 60090 C363 G T T T L T D C L R R F T R P
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVR1 735 82440 G572 W D I S L D L G E T T T H G G
Honey Bee Apis mellifera XP_392493 643 70321 S481 L D P F W D L S L P I P A R S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32571 926 105173 S749 Y Q P F T V L S I P I P K K N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.6 92.4 N.A. 88.9 38.5 N.A. 43.1 49.7 23.7 N.A. N.A. 24.6 37.1 N.A. N.A.
Protein Similarity: 100 99.5 98.1 94.3 N.A. 92.3 54 N.A. 46.2 54.2 38.6 N.A. N.A. 38.7 54.9 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. 0 6.6 13.3 N.A. N.A. 26.6 73.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 13.3 13.3 13.3 N.A. N.A. 33.3 73.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 42 17 0 0 % A
% Cys: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 9 67 0 9 9 59 9 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % E
% Phe: 42 0 9 59 0 9 0 0 0 0 0 17 0 0 0 % F
% Gly: 9 0 9 0 0 0 0 17 0 0 9 0 0 25 59 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 9 9 0 0 0 9 0 9 9 59 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 9 9 9 9 59 9 0 % K
% Leu: 9 0 9 0 34 9 67 9 59 0 0 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 9 59 0 0 9 0 9 9 59 9 17 0 0 9 % P
% Gln: 0 9 0 0 0 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 9 9 0 0 59 0 % R
% Ser: 0 0 0 17 0 0 9 59 0 0 0 9 9 0 9 % S
% Thr: 0 9 9 9 9 9 0 0 0 9 9 9 9 0 9 % T
% Val: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % V
% Trp: 9 0 0 9 50 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _