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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP2 All Species: 26.67
Human Site: T588 Identified Species: 53.33
UniProt: O75604 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75604 NP_004196.4 605 68072 T588 M S S S Q V R T S D A Y L L F
Chimpanzee Pan troglodytes XP_508813 605 67980 T588 M S S S Q V R T S D A Y L L F
Rhesus Macaque Macaca mulatta XP_001105333 605 68108 T588 M S S S Q V R T S D A Y L L F
Dog Lupus familis XP_849718 606 68141 T589 M S S S Q V R T S D A Y L L F
Cat Felis silvestris
Mouse Mus musculus O88623 613 68827 T596 M S S S Q V R T S D A Y L L F
Rat Rattus norvegicus B2GUX4 565 62681 E549 E N Q V A S S E G Y V L F Y Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514295 291 33623 Y275 M G G H Y T A Y C R S P V T G
Chicken Gallus gallus O57429 357 40913 S340 M S S S H V R S S D A Y L L F
Frog Xenopus laevis Q6DCJ1 523 60090 D507 A S I K D V I D S E G Y L L F
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVR1 735 82440 D719 A S L K Q V L D S E G Y L L F
Honey Bee Apis mellifera XP_392493 643 70321 S626 V P A R S V V S N E A Y V L F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32571 926 105173 A910 P V K N K A D A I N S N A Y V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.6 92.4 N.A. 88.9 38.5 N.A. 43.1 49.7 23.7 N.A. N.A. 24.6 37.1 N.A. N.A.
Protein Similarity: 100 99.5 98.1 94.3 N.A. 92.3 54 N.A. 46.2 54.2 38.6 N.A. N.A. 38.7 54.9 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 6.6 86.6 46.6 N.A. N.A. 53.3 33.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 6.6 N.A. 20 93.3 53.3 N.A. N.A. 60 73.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 9 0 9 9 9 9 0 0 59 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 9 17 0 50 0 0 0 0 0 % D
% Glu: 9 0 0 0 0 0 0 9 0 25 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 75 % F
% Gly: 0 9 9 0 0 0 0 0 9 0 17 0 0 0 9 % G
% His: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 0 9 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 9 17 9 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 9 0 0 0 9 0 0 0 0 9 67 75 0 % L
% Met: 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 9 0 0 0 0 9 9 0 9 0 0 0 % N
% Pro: 9 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % P
% Gln: 0 0 9 0 50 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 0 0 0 9 0 0 50 0 0 9 0 0 0 0 0 % R
% Ser: 0 67 50 50 9 9 9 17 67 0 17 0 0 0 0 % S
% Thr: 0 0 0 0 0 9 0 42 0 0 0 0 0 9 0 % T
% Val: 9 9 0 9 0 75 9 0 0 0 9 0 17 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 9 0 9 0 75 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _