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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP2
All Species:
20
Human Site:
Y450
Identified Species:
40
UniProt:
O75604
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75604
NP_004196.4
605
68072
Y450
L
P
I
A
K
R
G
Y
P
E
V
T
L
M
D
Chimpanzee
Pan troglodytes
XP_508813
605
67980
Y450
L
P
I
A
K
R
G
Y
P
E
V
T
L
M
D
Rhesus Macaque
Macaca mulatta
XP_001105333
605
68108
Y450
L
P
I
A
K
R
G
Y
P
E
V
T
L
M
D
Dog
Lupus familis
XP_849718
606
68141
Y451
L
P
I
A
K
R
G
Y
P
E
V
T
L
T
D
Cat
Felis silvestris
Mouse
Mus musculus
O88623
613
68827
Y458
L
P
I
A
K
R
G
Y
P
E
V
T
L
M
D
Rat
Rattus norvegicus
B2GUX4
565
62681
K413
K
K
G
F
A
G
G
K
V
S
L
R
D
C
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514295
291
33623
C139
Q
M
K
S
S
L
T
C
T
E
C
G
Y
C
S
Chicken
Gallus gallus
O57429
357
40913
G203
P
I
P
K
K
G
Y
G
E
V
T
L
M
D
C
Frog
Xenopus laevis
Q6DCJ1
523
60090
E371
L
R
R
F
T
R
P
E
H
L
G
S
S
A
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
V580
E
T
T
T
H
G
G
V
T
P
K
T
L
I
D
Honey Bee
Apis mellifera
XP_392493
643
70321
G489
L
P
I
P
A
R
S
G
T
V
K
L
S
Q
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32571
926
105173
S757
I
P
I
P
K
K
N
S
R
N
N
I
T
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.6
92.4
N.A.
88.9
38.5
N.A.
43.1
49.7
23.7
N.A.
N.A.
24.6
37.1
N.A.
N.A.
Protein Similarity:
100
99.5
98.1
94.3
N.A.
92.3
54
N.A.
46.2
54.2
38.6
N.A.
N.A.
38.7
54.9
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
6.6
N.A.
6.6
6.6
13.3
N.A.
N.A.
26.6
26.6
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
13.3
N.A.
13.3
13.3
20
N.A.
N.A.
33.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
42
17
0
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
9
0
0
17
17
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
50
% D
% Glu:
9
0
0
0
0
0
0
9
9
50
0
0
0
0
9
% E
% Phe:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
9
0
0
25
59
17
0
0
9
9
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
9
9
59
0
0
0
0
0
0
0
0
9
0
17
0
% I
% Lys:
9
9
9
9
59
9
0
9
0
0
17
0
0
0
9
% K
% Leu:
59
0
0
0
0
9
0
0
0
9
9
17
50
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
9
34
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
9
9
0
0
0
0
% N
% Pro:
9
59
9
17
0
0
9
0
42
9
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
9
9
0
0
59
0
0
9
0
0
9
0
0
0
% R
% Ser:
0
0
0
9
9
0
9
9
0
9
0
9
17
0
9
% S
% Thr:
0
9
9
9
9
0
9
0
25
0
9
50
9
9
0
% T
% Val:
0
0
0
0
0
0
0
9
9
17
42
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
42
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _