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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP2 All Species: 9.7
Human Site: Y74 Identified Species: 19.39
UniProt: O75604 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75604 NP_004196.4 605 68072 Y74 G P S S L L D Y D R G R P L L
Chimpanzee Pan troglodytes XP_508813 605 67980 Y74 G P S S L L D Y D R G R P L L
Rhesus Macaque Macaca mulatta XP_001105333 605 68108 Y74 G P S S I L D Y D R G R P L L
Dog Lupus familis XP_849718 606 68141 D75 P S S L L D Y D R G R P L L R
Cat Felis silvestris
Mouse Mus musculus O88623 613 68827 R82 D R G R P L L R S D I I G S S
Rat Rattus norvegicus B2GUX4 565 62681 L52 P N S M L R P L P P R P G P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514295 291 33623
Chicken Gallus gallus O57429 357 40913
Frog Xenopus laevis Q6DCJ1 523 60090 N10 P A G C S H V N S F K V E N W
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVR1 735 82440 R201 L D A T K H L R L S D C L R T
Honey Bee Apis mellifera XP_392493 643 70321 S112 S A Y S S T G S G S G T G T N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32571 926 105173 C232 I D T K N I I C L E P I S F K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.6 92.4 N.A. 88.9 38.5 N.A. 43.1 49.7 23.7 N.A. N.A. 24.6 37.1 N.A. N.A.
Protein Similarity: 100 99.5 98.1 94.3 N.A. 92.3 54 N.A. 46.2 54.2 38.6 N.A. N.A. 38.7 54.9 N.A. N.A.
P-Site Identity: 100 100 93.3 20 N.A. 6.6 13.3 N.A. 0 0 0 N.A. N.A. 0 13.3 N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 6.6 13.3 N.A. 0 0 0 N.A. N.A. 13.3 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 9 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 9 0 0 0 9 0 0 0 9 0 0 0 % C
% Asp: 9 17 0 0 0 9 25 9 25 9 9 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % F
% Gly: 25 0 17 0 0 0 9 0 9 9 34 0 25 0 0 % G
% His: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 9 9 9 0 0 0 9 17 0 0 0 % I
% Lys: 0 0 0 9 9 0 0 0 0 0 9 0 0 0 9 % K
% Leu: 9 0 0 9 34 34 17 9 17 0 0 0 17 34 25 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 9 0 0 9 0 0 0 0 0 9 9 % N
% Pro: 25 25 0 0 9 0 9 0 9 9 9 17 25 9 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 9 0 9 0 17 9 25 17 25 0 9 9 % R
% Ser: 9 9 42 34 17 0 0 9 17 17 0 0 9 9 9 % S
% Thr: 0 0 9 9 0 9 0 0 0 0 0 9 0 9 9 % T
% Val: 0 0 0 0 0 0 9 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 9 0 0 0 9 25 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _