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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYPLA1
All Species:
17.58
Human Site:
S165
Identified Species:
32.22
UniProt:
O75608
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75608
NP_006321.1
230
24670
S165
G
G
A
N
R
D
I
S
I
L
Q
C
H
G
D
Chimpanzee
Pan troglodytes
XP_519760
230
24713
S165
G
G
A
N
R
D
I
S
I
L
Q
C
H
G
D
Rhesus Macaque
Macaca mulatta
XP_001083287
230
24697
S165
G
G
A
N
R
D
I
S
I
L
Q
C
H
G
D
Dog
Lupus familis
XP_851288
216
23775
A164
L
K
T
L
V
N
P
A
N
V
T
F
K
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTL7
231
24775
I168
G
S
A
K
D
L
A
I
L
Q
C
H
G
E
L
Rat
Rattus norvegicus
P70470
230
24690
S165
N
S
A
N
R
D
I
S
V
L
Q
C
H
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514539
223
23982
S158
S
G
V
N
K
D
I
S
I
L
Q
C
H
G
E
Chicken
Gallus gallus
NP_001155854
232
25095
A168
N
G
V
N
K
D
I
A
I
L
Q
C
H
G
E
Frog
Xenopus laevis
NP_001085785
230
24436
A165
N
S
A
N
K
D
V
A
V
L
Q
C
H
G
E
Zebra Danio
Brachydanio rerio
NP_957043
232
25049
P168
A
S
A
N
K
D
T
P
I
L
Q
C
H
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392725
219
23829
L160
G
N
K
N
T
P
L
L
Q
C
H
G
D
C
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12354
227
24682
I165
G
I
N
V
K
T
P
I
F
H
G
H
G
D
M
Red Bread Mold
Neurospora crassa
Q9HFJ5
245
26967
T172
K
P
E
F
N
K
E
T
P
I
F
M
A
H
G
Conservation
Percent
Protein Identity:
100
99.1
98.6
73.9
N.A.
67.9
92.1
N.A.
76
68.5
80.8
68.9
N.A.
N.A.
53.9
N.A.
N.A.
Protein Similarity:
100
99.5
99.5
79.1
N.A.
81.3
95.6
N.A.
86
82.3
91.3
81.4
N.A.
N.A.
66.9
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
13.3
80
N.A.
73.3
66.6
53.3
60
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
20
86.6
N.A.
86.6
86.6
86.6
73.3
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.3
40.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.1
58.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
54
0
0
0
8
24
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
8
62
0
8
0
% C
% Asp:
0
0
0
0
8
62
0
0
0
0
0
0
8
8
39
% D
% Glu:
0
0
8
0
0
0
8
0
0
0
0
0
0
8
31
% E
% Phe:
0
0
0
8
0
0
0
0
8
0
8
8
0
0
0
% F
% Gly:
47
39
0
0
0
0
0
0
0
0
8
8
16
62
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
8
16
62
8
0
% H
% Ile:
0
8
0
0
0
0
47
16
47
8
0
0
0
0
0
% I
% Lys:
8
8
8
8
39
8
0
0
0
0
0
0
8
0
0
% K
% Leu:
8
0
0
8
0
8
8
8
8
62
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% M
% Asn:
24
8
8
70
8
8
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
8
16
8
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
8
62
0
0
0
0
% Q
% Arg:
0
0
0
0
31
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
31
0
0
0
0
0
39
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
8
8
8
8
0
0
8
0
0
8
0
% T
% Val:
0
0
16
8
8
0
8
0
16
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _