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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYPLA1
All Species:
34.24
Human Site:
S209
Identified Species:
62.78
UniProt:
O75608
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75608
NP_006321.1
230
24670
S209
T
Y
E
G
M
M
H
S
S
C
Q
Q
E
M
M
Chimpanzee
Pan troglodytes
XP_519760
230
24713
S209
T
Y
E
G
M
M
H
S
S
C
Q
Q
E
M
M
Rhesus Macaque
Macaca mulatta
XP_001083287
230
24697
S209
T
Y
E
G
M
M
H
S
S
C
Q
Q
E
M
M
Dog
Lupus familis
XP_851288
216
23775
R206
S
L
S
N
L
I
Q
R
I
F
T
V
P
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTL7
231
24775
S211
T
Y
P
G
V
M
H
S
S
C
P
Q
E
M
A
Rat
Rattus norvegicus
P70470
230
24690
S209
V
Y
E
G
M
M
H
S
S
C
Q
Q
E
M
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514539
223
23982
S202
T
Y
G
G
M
V
H
S
S
C
S
Q
E
M
M
Chicken
Gallus gallus
NP_001155854
232
25095
N212
T
Y
P
G
V
M
H
N
S
C
P
Q
E
M
M
Frog
Xenopus laevis
NP_001085785
230
24436
S209
T
Y
S
G
L
M
H
S
S
C
N
Q
E
M
T
Zebra Danio
Brachydanio rerio
NP_957043
232
25049
S212
T
Y
P
G
L
M
H
S
S
C
P
Q
E
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392725
219
23829
K211
E
E
M
R
D
M
K
K
F
I
E
K
V
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12354
227
24682
S208
V
Y
K
G
M
A
H
S
T
V
P
D
E
L
E
Red Bread Mold
Neurospora crassa
Q9HFJ5
245
26967
S215
T
Y
P
G
M
G
H
S
A
C
L
E
E
L
D
Conservation
Percent
Protein Identity:
100
99.1
98.6
73.9
N.A.
67.9
92.1
N.A.
76
68.5
80.8
68.9
N.A.
N.A.
53.9
N.A.
N.A.
Protein Similarity:
100
99.5
99.5
79.1
N.A.
81.3
95.6
N.A.
86
82.3
91.3
81.4
N.A.
N.A.
66.9
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
73.3
93.3
N.A.
80
73.3
73.3
73.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
80
93.3
N.A.
86.6
86.6
80
80
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.3
40.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.1
58.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
77
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
8
% D
% Glu:
8
8
31
0
0
0
0
0
0
0
8
8
85
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% F
% Gly:
0
0
8
85
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
85
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
8
8
0
0
0
8
0
% I
% Lys:
0
0
8
0
0
0
8
8
0
0
0
8
0
0
8
% K
% Leu:
0
8
0
0
24
0
0
0
0
0
8
0
0
24
0
% L
% Met:
0
0
8
0
54
70
0
0
0
0
0
0
0
70
47
% M
% Asn:
0
0
0
8
0
0
0
8
0
0
8
0
0
0
0
% N
% Pro:
0
0
31
0
0
0
0
0
0
0
31
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
31
70
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
0
16
0
0
0
0
77
70
0
8
0
0
0
8
% S
% Thr:
70
0
0
0
0
0
0
0
8
0
8
0
0
0
16
% T
% Val:
16
0
0
0
16
8
0
0
0
8
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
85
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _