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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LEFTY1 All Species: 17.58
Human Site: S161 Identified Species: 38.67
UniProt: O75610 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75610 NP_066277.1 366 40880 S161 D D G S N R T S L I D S R L V
Chimpanzee Pan troglodytes XP_001138066 366 40871 S161 D D G S N R T S L I D S R L V
Rhesus Macaque Macaca mulatta XP_001092296 366 40758 S161 D D G S N R T S L I D S R L V
Dog Lupus familis XP_547508 410 45569 S204 D D G P N R T S L V D S R L V
Cat Felis silvestris
Mouse Mus musculus P57785 368 41157 A161 E D G S N R T A L I D S R L V
Rat Rattus norvegicus Q4AEG6 421 47748 L184 S E D E R S M L V L V S T E I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512708 369 41483 F163 A D G T N R T F L V D S R P L
Chicken Gallus gallus Q90752 405 46039 R198 E R S Q A I T R L L D T R L V
Frog Xenopus laevis P25703 398 45557 R192 A S R G P V V R L L D T R L V
Zebra Danio Brachydanio rerio NP_571035 358 41023 S166 K D G S N R T S L V D S R L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001123281 399 44790 A177 S D P S D L A A E V V N Q H N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 93.7 71.9 N.A. 82 20.4 N.A. 43.3 20.4 20.8 35.7 N.A. N.A. N.A. N.A. 21.5
Protein Similarity: 100 98.9 95.6 79.2 N.A. 88.8 38 N.A. 60.1 36.7 36.6 58.2 N.A. N.A. N.A. N.A. 38.8
P-Site Identity: 100 100 100 86.6 N.A. 86.6 6.6 N.A. 60 40 33.3 80 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 100 33.3 N.A. 80 60 46.6 93.3 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 0 0 10 0 10 19 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 37 73 10 0 10 0 0 0 0 0 82 0 0 0 0 % D
% Glu: 19 10 0 10 0 0 0 0 10 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 64 10 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 37 0 0 0 0 19 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 10 0 10 82 28 0 0 0 73 10 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 64 0 0 0 0 0 0 10 0 0 10 % N
% Pro: 0 0 10 10 10 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 10 10 0 10 64 0 19 0 0 0 0 82 0 0 % R
% Ser: 19 10 10 55 0 10 0 46 0 0 0 73 0 0 0 % S
% Thr: 0 0 0 10 0 0 73 0 0 0 0 19 10 0 0 % T
% Val: 0 0 0 0 0 10 10 0 10 37 19 0 0 0 64 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _