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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEFTY1
All Species:
20
Human Site:
S202
Identified Species:
44
UniProt:
O75610
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75610
NP_066277.1
366
40880
S202
Q
P
L
L
L
Q
V
S
V
Q
R
E
H
L
G
Chimpanzee
Pan troglodytes
XP_001138066
366
40871
S202
Q
P
L
L
L
Q
V
S
V
Q
R
E
H
L
G
Rhesus Macaque
Macaca mulatta
XP_001092296
366
40758
S202
P
P
L
L
L
Q
V
S
V
Q
R
E
H
L
G
Dog
Lupus familis
XP_547508
410
45569
S245
Q
P
L
L
L
Q
V
S
V
Q
R
E
H
L
G
Cat
Felis silvestris
Mouse
Mus musculus
P57785
368
41157
S202
Q
P
L
L
L
Q
V
S
V
Q
R
E
H
L
G
Rat
Rattus norvegicus
Q4AEG6
421
47748
E225
H
Q
L
E
I
H
I
E
S
R
Q
N
Q
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512708
369
41483
R204
D
P
M
L
L
G
I
R
I
R
G
D
G
A
G
Chicken
Gallus gallus
Q90752
405
46039
T239
H
G
L
V
I
E
V
T
H
L
H
Q
A
Q
T
Frog
Xenopus laevis
P25703
398
45557
N233
H
G
F
V
V
E
V
N
H
L
D
N
D
K
N
Zebra Danio
Brachydanio rerio
NP_571035
358
41023
I207
P
M
H
L
E
V
W
I
E
G
E
R
P
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123281
399
44790
D218
T
I
Q
T
W
V
A
D
P
D
S
N
L
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
93.7
71.9
N.A.
82
20.4
N.A.
43.3
20.4
20.8
35.7
N.A.
N.A.
N.A.
N.A.
21.5
Protein Similarity:
100
98.9
95.6
79.2
N.A.
88.8
38
N.A.
60.1
36.7
36.6
58.2
N.A.
N.A.
N.A.
N.A.
38.8
P-Site Identity:
100
100
93.3
100
N.A.
100
6.6
N.A.
26.6
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
100
N.A.
100
33.3
N.A.
60
46.6
33.3
6.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
10
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
10
0
10
10
10
10
0
0
% D
% Glu:
0
0
0
10
10
19
0
10
10
0
10
46
0
0
10
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
19
0
0
0
10
0
0
0
10
10
0
10
19
55
% G
% His:
28
0
10
0
0
10
0
0
19
0
10
0
46
0
0
% H
% Ile:
0
10
0
0
19
0
19
10
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
64
64
55
0
0
0
0
19
0
0
10
46
0
% L
% Met:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
28
0
0
10
% N
% Pro:
19
55
0
0
0
0
0
0
10
0
0
0
10
0
0
% P
% Gln:
37
10
10
0
0
46
0
0
0
46
10
10
10
10
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
19
46
10
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
46
10
0
10
0
0
0
10
% S
% Thr:
10
0
0
10
0
0
0
10
0
0
0
0
0
0
10
% T
% Val:
0
0
0
19
10
19
64
0
46
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _