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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEFTY1
All Species:
8.79
Human Site:
S81
Identified Species:
19.33
UniProt:
O75610
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75610
NP_066277.1
366
40880
S81
R
G
K
R
F
S
Q
S
F
R
E
V
A
G
R
Chimpanzee
Pan troglodytes
XP_001138066
366
40871
S81
R
G
K
R
F
S
Q
S
F
R
E
V
A
G
R
Rhesus Macaque
Macaca mulatta
XP_001092296
366
40758
S81
R
G
K
R
F
S
H
S
F
R
E
V
A
G
R
Dog
Lupus familis
XP_547508
410
45569
R124
R
G
K
R
F
S
Q
R
F
R
E
V
A
G
R
Cat
Felis silvestris
Mouse
Mus musculus
P57785
368
41157
N81
R
G
K
R
F
S
Q
N
F
R
E
V
A
G
R
Rat
Rattus norvegicus
Q4AEG6
421
47748
I104
T
S
M
P
S
A
N
I
I
R
S
F
K
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512708
369
41483
A80
S
R
G
K
R
S
H
A
S
I
R
E
I
V
G
Chicken
Gallus gallus
Q90752
405
46039
A112
L
Q
Y
P
E
R
S
A
S
R
A
N
T
V
R
Frog
Xenopus laevis
P25703
398
45557
D79
V
I
P
P
Y
M
L
D
L
Y
H
L
H
L
A
Zebra Danio
Brachydanio rerio
NP_571035
358
41023
G80
R
S
L
P
S
L
A
G
I
L
R
G
I
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123281
399
44790
K86
Y
I
T
K
G
I
H
K
N
E
E
I
Y
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
93.7
71.9
N.A.
82
20.4
N.A.
43.3
20.4
20.8
35.7
N.A.
N.A.
N.A.
N.A.
21.5
Protein Similarity:
100
98.9
95.6
79.2
N.A.
88.8
38
N.A.
60.1
36.7
36.6
58.2
N.A.
N.A.
N.A.
N.A.
38.8
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
6.6
N.A.
6.6
13.3
0
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
100
13.3
N.A.
20
20
13.3
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
19
0
0
10
0
46
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
10
55
10
0
0
19
% E
% Phe:
0
0
0
0
46
0
0
0
46
0
0
10
0
0
0
% F
% Gly:
0
46
10
0
10
0
0
10
0
0
0
10
0
55
19
% G
% His:
0
0
0
0
0
0
28
0
0
0
10
0
10
0
0
% H
% Ile:
0
19
0
0
0
10
0
10
19
10
0
10
19
0
0
% I
% Lys:
0
0
46
19
0
0
0
10
0
0
0
0
10
0
0
% K
% Leu:
10
0
10
0
0
10
10
0
10
10
0
10
0
10
0
% L
% Met:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
10
10
0
0
10
0
10
0
% N
% Pro:
0
0
10
37
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
10
0
0
0
0
37
0
0
0
0
0
0
0
0
% Q
% Arg:
55
10
0
46
10
10
0
10
0
64
19
0
0
0
55
% R
% Ser:
10
19
0
0
19
55
10
28
19
0
10
0
0
0
0
% S
% Thr:
10
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
46
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
0
10
0
0
0
0
10
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _