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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LEFTY1 All Species: 12.12
Human Site: T42 Identified Species: 26.67
UniProt: O75610 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75610 NP_066277.1 366 40880 T42 L Q L K E V P T L D R A D M E
Chimpanzee Pan troglodytes XP_001138066 366 40871 T42 L Q L R E V P T L D R A D M E
Rhesus Macaque Macaca mulatta XP_001092296 366 40758 V42 L Q L S E V P V P D R V D M E
Dog Lupus familis XP_547508 410 45569 V85 L H L S Q V P V L D E G D V E
Cat Felis silvestris
Mouse Mus musculus P57785 368 41157 T42 L Q L S Q A P T L D S A D V E
Rat Rattus norvegicus Q4AEG6 421 47748 T65 M K D E F L K T L N L S D I P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512708 369 41483 V41 L S L K E P P V L D K A E L G
Chicken Gallus gallus Q90752 405 46039 Q73 F G L R R R P Q P S K S A V I
Frog Xenopus laevis P25703 398 45557 S40 Y T E S G R S S P Q Q S Q R V
Zebra Danio Brachydanio rerio NP_571035 358 41023 Q41 L G L N E I P Q I H K R D L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001123281 399 44790 N47 I G V T N P W N F P S V D A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 93.7 71.9 N.A. 82 20.4 N.A. 43.3 20.4 20.8 35.7 N.A. N.A. N.A. N.A. 21.5
Protein Similarity: 100 98.9 95.6 79.2 N.A. 88.8 38 N.A. 60.1 36.7 36.6 58.2 N.A. N.A. N.A. N.A. 38.8
P-Site Identity: 100 93.3 73.3 53.3 N.A. 66.6 20 N.A. 53.3 13.3 0 40 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 73.3 66.6 N.A. 80 66.6 N.A. 73.3 40 20 66.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 0 0 0 37 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 55 0 0 73 0 0 % D
% Glu: 0 0 10 10 46 0 0 0 0 0 10 0 10 0 55 % E
% Phe: 10 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 28 0 0 10 0 0 0 0 0 0 10 0 0 10 % G
% His: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 10 0 0 10 0 0 0 0 10 10 % I
% Lys: 0 10 0 19 0 0 10 0 0 0 28 0 0 0 0 % K
% Leu: 64 0 73 0 0 10 0 0 55 0 10 0 0 19 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 28 0 % M
% Asn: 0 0 0 10 10 0 0 10 0 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 19 73 0 28 10 0 0 0 0 10 % P
% Gln: 0 37 0 0 19 0 0 19 0 10 10 0 10 0 0 % Q
% Arg: 0 0 0 19 10 19 0 0 0 0 28 10 0 10 0 % R
% Ser: 0 10 0 37 0 0 10 10 0 10 19 28 0 0 10 % S
% Thr: 0 10 0 10 0 0 0 37 0 0 0 0 0 0 0 % T
% Val: 0 0 10 0 0 37 0 28 0 0 0 19 0 28 10 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _