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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEFTY1
All Species:
23.94
Human Site:
Y291
Identified Species:
52.67
UniProt:
O75610
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75610
NP_066277.1
366
40880
Y291
E
P
P
G
F
L
A
Y
E
C
V
G
T
C
R
Chimpanzee
Pan troglodytes
XP_001138066
366
40871
Y291
E
P
P
G
F
L
A
Y
E
C
V
G
T
C
R
Rhesus Macaque
Macaca mulatta
XP_001092296
366
40758
Y291
E
P
P
G
F
L
A
Y
E
C
V
G
T
C
Q
Dog
Lupus familis
XP_547508
410
45569
Y335
E
P
P
G
F
L
A
Y
E
C
V
G
T
C
Q
Cat
Felis silvestris
Mouse
Mus musculus
P57785
368
41157
Y293
E
P
P
G
F
L
T
Y
E
C
V
G
S
C
L
Rat
Rattus norvegicus
Q4AEG6
421
47748
Y347
A
P
P
G
Y
E
A
Y
E
C
R
G
V
C
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512708
369
41483
Y289
E
P
P
I
L
Q
L
Y
D
C
V
G
S
C
R
Chicken
Gallus gallus
Q90752
405
46039
F332
A
P
P
G
Y
Q
A
F
Y
C
H
G
D
C
P
Frog
Xenopus laevis
P25703
398
45557
F325
A
P
P
G
Y
H
A
F
Y
C
H
G
E
C
P
Zebra Danio
Brachydanio rerio
NP_571035
358
41023
F293
E
P
S
G
Y
Q
A
F
R
C
K
G
G
C
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123281
399
44790
F319
E
P
A
G
F
E
A
F
D
C
Y
G
P
C
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
93.7
71.9
N.A.
82
20.4
N.A.
43.3
20.4
20.8
35.7
N.A.
N.A.
N.A.
N.A.
21.5
Protein Similarity:
100
98.9
95.6
79.2
N.A.
88.8
38
N.A.
60.1
36.7
36.6
58.2
N.A.
N.A.
N.A.
N.A.
38.8
P-Site Identity:
100
100
93.3
93.3
N.A.
80
60
N.A.
60
46.6
46.6
53.3
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
66.6
N.A.
73.3
60
60
66.6
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
0
10
0
0
0
82
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
100
0
0
0
100
0
% C
% Asp:
0
0
0
0
0
0
0
0
19
0
0
0
10
0
0
% D
% Glu:
73
0
0
0
0
19
0
0
55
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
55
0
0
37
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
91
0
0
0
0
0
0
0
100
10
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
19
0
0
0
10
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
10
46
10
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
100
82
0
0
0
0
0
0
0
0
0
10
0
19
% P
% Gln:
0
0
0
0
0
28
0
0
0
0
0
0
0
0
19
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
37
% R
% Ser:
0
0
10
0
0
0
0
0
0
0
0
0
19
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
37
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
55
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
37
0
0
64
19
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _