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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LEFTY1 All Species: 29.09
Human Site: Y61 Identified Species: 64
UniProt: O75610 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75610 NP_066277.1 366 40880 Y61 P T H V R A Q Y V A L L Q R S
Chimpanzee Pan troglodytes XP_001138066 366 40871 Y61 P T H V R A Q Y V A L L Q R S
Rhesus Macaque Macaca mulatta XP_001092296 366 40758 Y61 P A H V R A Q Y V A L L R R S
Dog Lupus familis XP_547508 410 45569 Y104 P A H V T A Q Y V A L L R R S
Cat Felis silvestris
Mouse Mus musculus P57785 368 41157 Y61 P T H V R S Q Y V A L L Q G S
Rat Rattus norvegicus Q4AEG6 421 47748 Y84 G R V D P P E Y M L E L Y N K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512708 369 41483 Y60 S D P L R S D Y L R R L R Q S
Chicken Gallus gallus Q90752 405 46039 S92 L D L Y R L Q S G E E E E R S
Frog Xenopus laevis P25703 398 45557 F59 E L R L L S M F G L K R R P T
Zebra Danio Brachydanio rerio NP_571035 358 41023 Y60 P T H V K N K Y I S M L K L H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001123281 399 44790 Y66 P D H L R F Q Y E S L H R Q H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 93.7 71.9 N.A. 82 20.4 N.A. 43.3 20.4 20.8 35.7 N.A. N.A. N.A. N.A. 21.5
Protein Similarity: 100 98.9 95.6 79.2 N.A. 88.8 38 N.A. 60.1 36.7 36.6 58.2 N.A. N.A. N.A. N.A. 38.8
P-Site Identity: 100 100 86.6 80 N.A. 86.6 13.3 N.A. 26.6 26.6 0 40 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 100 93.3 86.6 N.A. 93.3 26.6 N.A. 60 33.3 33.3 80 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 0 0 0 37 0 0 0 46 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 28 0 10 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 0 10 0 10 10 19 10 10 0 0 % E
% Phe: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 19 0 0 0 0 10 0 % G
% His: 0 0 64 0 0 0 0 0 0 0 0 10 0 0 19 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 0 10 0 0 0 10 0 10 0 10 % K
% Leu: 10 10 10 28 10 10 0 0 10 19 55 73 0 10 0 % L
% Met: 0 0 0 0 0 0 10 0 10 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % N
% Pro: 64 0 10 0 10 10 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 64 0 0 0 0 0 28 19 0 % Q
% Arg: 0 10 10 0 64 0 0 0 0 10 10 10 46 46 0 % R
% Ser: 10 0 0 0 0 28 0 10 0 19 0 0 0 0 64 % S
% Thr: 0 37 0 0 10 0 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 10 55 0 0 0 0 46 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 82 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _