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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEDD
All Species:
23.64
Human Site:
S175
Identified Species:
65
UniProt:
O75618
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75618
NP_001034800.1
318
36794
S175
R
G
R
A
T
L
G
S
Q
R
K
R
R
K
S
Chimpanzee
Pan troglodytes
XP_001172953
348
40386
S175
R
G
R
A
T
L
G
S
Q
R
K
R
R
K
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545766
318
36786
S175
R
G
R
A
T
L
G
S
Q
R
K
R
R
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1L3
318
36787
S175
R
G
R
T
T
L
G
S
Q
R
K
R
R
K
S
Rat
Rattus norvegicus
Q9Z2K0
318
36829
S175
R
G
R
T
T
L
G
S
Q
R
K
R
R
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520660
116
12937
Chicken
Gallus gallus
XP_423146
318
36729
S175
R
G
R
A
L
L
S
S
Q
R
K
R
R
K
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002639
404
44870
S250
K
P
A
P
P
P
P
S
R
K
R
K
R
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198205
159
18300
K35
M
P
F
V
T
R
R
K
R
K
R
D
I
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
N.A.
99.6
N.A.
98.7
98.4
N.A.
25.1
88.6
N.A.
59.9
N.A.
N.A.
N.A.
N.A.
36.4
Protein Similarity:
100
91.3
N.A.
99.6
N.A.
99
98.7
N.A.
28.9
93.4
N.A.
67.3
N.A.
N.A.
N.A.
N.A.
42.7
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
0
86.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
0
86.6
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
45
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
67
0
0
0
0
56
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% I
% Lys:
12
0
0
0
0
0
0
12
0
23
67
12
0
67
0
% K
% Leu:
0
0
0
0
12
67
0
0
0
0
0
0
0
0
12
% L
% Met:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
23
0
12
12
12
12
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% Q
% Arg:
67
0
67
0
0
12
12
0
23
67
23
67
78
12
0
% R
% Ser:
0
0
0
0
0
0
12
78
0
0
0
0
0
12
67
% S
% Thr:
0
0
0
23
67
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _