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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRDM1 All Species: 15.76
Human Site: Y374 Identified Species: 31.52
UniProt: O75626 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75626 NP_001189.2 789 87991 Y374 S Q E H R D S Y A Y L N A S Y
Chimpanzee Pan troglodytes XP_518658 825 91729 Y374 S Q E H R D S Y A Y L N A P Y
Rhesus Macaque Macaca mulatta XP_001087708 825 91728 Y374 S Q E H R D S Y A Y L N A P Y
Dog Lupus familis XP_539068 1176 127325 L725 H R D S Y A Y L N A P Y G P E
Cat Felis silvestris
Mouse Mus musculus Q60636 856 95818 Y406 L P E H R D S Y S Y L N V S Y
Rat Rattus norvegicus Q4KLI1 562 63347 L131 G E E A V T L L E D L E L D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505433 791 87433 Y339 T Q E H R E P Y P F V G A P Y
Chicken Gallus gallus
Frog Xenopus laevis NP_001080573 780 88065 N338 K E F Y P F I N R P Y N T E G
Zebra Danio Brachydanio rerio NP_955809 776 87319 F333 S I E P R E A F L P F S P A L
Tiger Blowfish Takifugu rubipres NP_001027861 785 87126 G333 P F P F Y P P G L T S Y P G Y
Fruit Fly Dros. melanogaster NP_647982 1203 133262 S415 G S V R S V R S D E G Y H S N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_492723 817 88621 V345 Q N P V V R P V A T K V N N F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 99 59.9 N.A. 85.4 21.8 N.A. 75.6 N.A. 66.9 55.7 48.6 26.3 N.A. 21.4 N.A.
Protein Similarity: 100 99.3 99.5 63.1 N.A. 90.5 35.2 N.A. 84.6 N.A. 78.7 68 61.7 39.9 N.A. 37.7 N.A.
P-Site Identity: 100 93.3 93.3 0 N.A. 73.3 13.3 N.A. 46.6 N.A. 6.6 20 6.6 6.6 N.A. 6.6 N.A.
P-Site Similarity: 100 93.3 93.3 13.3 N.A. 80 20 N.A. 73.3 N.A. 20 53.3 6.6 6.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 9 9 0 34 9 0 0 34 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 34 0 0 9 9 0 0 0 9 0 % D
% Glu: 0 17 59 0 0 17 0 0 9 9 0 9 0 9 9 % E
% Phe: 0 9 9 9 0 9 0 9 0 9 9 0 0 0 9 % F
% Gly: 17 0 0 0 0 0 0 9 0 0 9 9 9 9 9 % G
% His: 9 0 0 42 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % K
% Leu: 9 0 0 0 0 0 9 17 17 0 42 0 9 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 9 9 0 0 42 9 9 9 % N
% Pro: 9 9 17 9 9 9 25 0 9 17 9 0 17 34 0 % P
% Gln: 9 34 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 9 50 9 9 0 9 0 0 0 0 0 0 % R
% Ser: 34 9 0 9 9 0 34 9 9 0 9 9 0 25 0 % S
% Thr: 9 0 0 0 0 9 0 0 0 17 0 0 9 0 0 % T
% Val: 0 0 9 9 17 9 0 9 0 0 9 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 17 0 9 42 0 34 9 25 0 0 50 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _