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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CREG1 All Species: 26.97
Human Site: S100 Identified Species: 49.44
UniProt: O75629 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75629 NP_003842.1 220 24075 S100 D G P P G A G S G V P Y F Y L
Chimpanzee Pan troglodytes XP_001157266 335 36715 S215 D G P P G A G S G V P Y F Y L
Rhesus Macaque Macaca mulatta XP_001089325 220 24080 S100 D G P P G A G S G V P Y F Y L
Dog Lupus familis XP_854297 180 20555 I60 P L D N S T G I P F F Y V T P
Cat Felis silvestris
Mouse Mus musculus O88668 220 24433 T100 D G P P G E G T G E P Y M Y L
Rat Rattus norvegicus NP_001099436 220 24369 S100 D G P P G E G S G E P Y M Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJ73 192 21088 S73 A P G P G G G S G V P Y L Y L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001074159 207 22893 S88 Y L T H L D I S V Q D L Q V N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624302 290 33697 S131 D G L L G N G S G I P Y L Y L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796937 218 23864 S94 D G A L G K S S G T P Y F Y L
Poplar Tree Populus trichocarpa XP_002299070 191 21144 G72 S D G L P G K G S G I P Y F Y
Maize Zea mays NP_001148752 210 22772 T91 G I P Y F Y L T T L D P S A R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_178546 210 23576 Y91 G N G I P Y F Y L T T L D P T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.7 96.8 32.2 N.A. 76.8 76.8 N.A. N.A. 55.4 N.A. 50.4 N.A. N.A. 30 N.A. 36.8
Protein Similarity: 100 65.3 98.6 50.4 N.A. 87.2 85.4 N.A. N.A. 70.4 N.A. 69.5 N.A. N.A. 45.8 N.A. 55.4
P-Site Identity: 100 100 100 13.3 N.A. 73.3 80 N.A. N.A. 66.6 N.A. 6.6 N.A. N.A. 66.6 N.A. 66.6
P-Site Similarity: 100 100 100 13.3 N.A. 80 80 N.A. N.A. 66.6 N.A. 6.6 N.A. N.A. 73.3 N.A. 66.6
Percent
Protein Identity: 35 36.3 N.A. 30.4 N.A. N.A.
Protein Similarity: 55 57.7 N.A. 52.7 N.A. N.A.
P-Site Identity: 0 6.6 N.A. 0 N.A. N.A.
P-Site Similarity: 13.3 20 N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 24 0 0 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 54 8 8 0 0 8 0 0 0 0 16 0 8 0 0 % D
% Glu: 0 0 0 0 0 16 0 0 0 16 0 0 0 0 0 % E
% Phe: 0 0 0 0 8 0 8 0 0 8 8 0 31 8 0 % F
% Gly: 16 54 24 0 62 16 62 8 62 8 0 0 0 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 8 0 0 8 8 0 8 8 0 0 0 0 % I
% Lys: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % K
% Leu: 0 16 8 24 8 0 8 0 8 8 0 16 16 0 62 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 0 % M
% Asn: 0 8 0 8 0 8 0 0 0 0 0 0 0 0 8 % N
% Pro: 8 8 47 47 16 0 0 0 8 0 62 16 0 8 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 8 0 0 0 8 0 8 62 8 0 0 0 8 0 0 % S
% Thr: 0 0 8 0 0 8 0 16 8 16 8 0 0 8 8 % T
% Val: 0 0 0 0 0 0 0 0 8 31 0 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 8 0 16 0 8 0 0 0 70 8 62 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _