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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CREG1 All Species: 20.91
Human Site: S113 Identified Species: 38.33
UniProt: O75629 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75629 NP_003842.1 220 24075 S113 Y L S P L Q L S V S N L Q E N
Chimpanzee Pan troglodytes XP_001157266 335 36715 S228 Y L S P L Q L S V S N L R E N
Rhesus Macaque Macaca mulatta XP_001089325 220 24080 S113 Y L S P L Q L S V N N L Q E N
Dog Lupus familis XP_854297 180 20555 A73 T P K D P A V A D L M K N P M
Cat Felis silvestris
Mouse Mus musculus O88668 220 24433 A113 Y L S P L Q Q A V S D L Q E N
Rat Rattus norvegicus NP_001099436 220 24369 A113 Y L S P L Q Q A V S D L Q G N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJ73 192 21088 S86 Y L T D M E I S V Q D L E V N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001074159 207 22893 S101 V N P Q V S L S M S L A Q S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624302 290 33697 T144 Y L T P L D F T A Q D L A K D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796937 218 23864 T107 Y L A E I D S T M Q D V A K N
Poplar Tree Populus trichocarpa XP_002299070 191 21144 P85 F Y L T T L D P T A K N A L Q
Maize Zea mays NP_001148752 210 22772 E104 A R D A L E D E R T S F T L S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_178546 210 23576 K104 P T A R N A L K D Q R A S L A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.7 96.8 32.2 N.A. 76.8 76.8 N.A. N.A. 55.4 N.A. 50.4 N.A. N.A. 30 N.A. 36.8
Protein Similarity: 100 65.3 98.6 50.4 N.A. 87.2 85.4 N.A. N.A. 70.4 N.A. 69.5 N.A. N.A. 45.8 N.A. 55.4
P-Site Identity: 100 93.3 93.3 0 N.A. 80 73.3 N.A. N.A. 40 N.A. 26.6 N.A. N.A. 33.3 N.A. 20
P-Site Similarity: 100 100 100 13.3 N.A. 93.3 86.6 N.A. N.A. 80 N.A. 46.6 N.A. N.A. 66.6 N.A. 66.6
Percent
Protein Identity: 35 36.3 N.A. 30.4 N.A. N.A.
Protein Similarity: 55 57.7 N.A. 52.7 N.A. N.A.
P-Site Identity: 0 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 33.3 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 16 8 0 16 0 24 8 8 0 16 24 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 16 0 16 16 0 16 0 39 0 0 0 8 % D
% Glu: 0 0 0 8 0 16 0 8 0 0 0 0 8 31 0 % E
% Phe: 8 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 8 0 0 8 8 0 16 0 % K
% Leu: 0 62 8 0 54 8 39 0 0 8 8 54 0 24 0 % L
% Met: 0 0 0 0 8 0 0 0 16 0 8 0 0 0 8 % M
% Asn: 0 8 0 0 8 0 0 0 0 8 24 8 8 0 54 % N
% Pro: 8 8 8 47 8 0 0 8 0 0 0 0 0 8 0 % P
% Gln: 0 0 0 8 0 39 16 0 0 31 0 0 39 0 8 % Q
% Arg: 0 8 0 8 0 0 0 0 8 0 8 0 8 0 0 % R
% Ser: 0 0 39 0 0 8 8 39 0 39 8 0 8 8 16 % S
% Thr: 8 8 16 8 8 0 0 16 8 8 0 0 8 0 0 % T
% Val: 8 0 0 0 8 0 8 0 47 0 0 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 62 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _