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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREG1
All Species:
9.09
Human Site:
S19
Identified Species:
16.67
UniProt:
O75629
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75629
NP_003842.1
220
24075
S19
L
L
A
A
L
L
A
S
T
L
L
A
L
L
V
Chimpanzee
Pan troglodytes
XP_001157266
335
36715
S134
L
L
A
A
L
L
A
S
T
L
L
A
L
L
V
Rhesus Macaque
Macaca mulatta
XP_001089325
220
24080
S19
L
L
A
A
L
L
A
S
T
L
L
A
L
L
V
Dog
Lupus familis
XP_854297
180
20555
Cat
Felis silvestris
Mouse
Mus musculus
O88668
220
24433
P19
L
L
A
A
L
L
A
P
A
L
V
A
L
L
V
Rat
Rattus norvegicus
NP_001099436
220
24369
P19
L
L
A
A
L
L
A
P
A
L
V
A
L
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJ73
192
21088
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074159
207
22893
L12
L
L
S
V
I
L
A
L
S
A
A
A
P
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624302
290
33697
E35
E
Q
W
Q
E
F
E
E
Y
M
K
W
K
K
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796937
218
23864
L19
S
C
C
V
S
A
V
L
S
D
I
Q
N
Q
L
Poplar Tree
Populus trichocarpa
XP_002299070
191
21144
Maize
Zea mays
NP_001148752
210
22772
V16
F
A
A
A
F
L
L
V
V
R
S
S
A
P
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_178546
210
23576
F16
R
P
I
F
F
F
F
F
F
V
F
L
T
I
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.7
96.8
32.2
N.A.
76.8
76.8
N.A.
N.A.
55.4
N.A.
50.4
N.A.
N.A.
30
N.A.
36.8
Protein Similarity:
100
65.3
98.6
50.4
N.A.
87.2
85.4
N.A.
N.A.
70.4
N.A.
69.5
N.A.
N.A.
45.8
N.A.
55.4
P-Site Identity:
100
100
100
0
N.A.
80
80
N.A.
N.A.
0
N.A.
33.3
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
0
N.A.
86.6
86.6
N.A.
N.A.
0
N.A.
60
N.A.
N.A.
6.6
N.A.
20
Percent
Protein Identity:
35
36.3
N.A.
30.4
N.A.
N.A.
Protein Similarity:
55
57.7
N.A.
52.7
N.A.
N.A.
P-Site Identity:
0
20
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
26.6
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
47
47
0
8
47
0
16
8
8
47
8
0
8
% A
% Cys:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
8
0
0
0
8
0
8
8
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
8
16
16
8
8
8
0
8
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
8
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
8
8
0
% K
% Leu:
47
47
0
0
39
54
8
16
0
39
24
8
39
39
16
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
8
0
0
0
0
0
16
0
0
0
0
8
8
0
% P
% Gln:
0
8
0
8
0
0
0
0
0
0
0
8
0
8
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
0
8
0
8
0
0
24
16
0
8
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
24
0
0
0
8
0
0
% T
% Val:
0
0
0
16
0
0
8
8
8
8
16
0
0
8
39
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _