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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREG1
All Species:
11.52
Human Site:
S44
Identified Species:
21.11
UniProt:
O75629
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75629
NP_003842.1
220
24075
S44
H
G
D
W
D
E
A
S
R
L
P
P
L
P
P
Chimpanzee
Pan troglodytes
XP_001157266
335
36715
S159
P
G
D
W
D
E
A
S
R
L
P
P
L
P
P
Rhesus Macaque
Macaca mulatta
XP_001089325
220
24080
S44
H
G
D
W
D
E
A
S
L
L
P
P
L
P
P
Dog
Lupus familis
XP_854297
180
20555
G8
M
F
S
Y
R
R
Q
G
G
P
R
L
R
P
G
Cat
Felis silvestris
Mouse
Mus musculus
O88668
220
24433
R44
H
G
D
W
D
V
D
R
R
L
P
P
L
P
P
Rat
Rattus norvegicus
NP_001099436
220
24369
R44
H
G
D
W
D
V
D
R
R
L
P
P
L
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJ73
192
21088
P21
A
L
A
R
G
T
I
P
P
P
E
E
A
A
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074159
207
22893
R35
E
Q
V
A
R
M
A
R
F
V
V
S
K
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624302
290
33697
Y66
Y
H
E
N
H
D
M
Y
K
S
P
K
K
D
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796937
218
23864
T42
A
E
Q
S
S
A
S
T
R
P
P
F
I
D
K
Poplar Tree
Populus trichocarpa
XP_002299070
191
21144
L20
D
S
V
Q
G
R
L
L
L
I
N
K
P
D
P
Maize
Zea mays
NP_001148752
210
22772
E39
D
G
K
P
S
P
S
E
A
T
A
T
A
R
W
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_178546
210
23576
R39
L
T
I
T
K
P
D
R
H
D
Y
A
A
S
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.7
96.8
32.2
N.A.
76.8
76.8
N.A.
N.A.
55.4
N.A.
50.4
N.A.
N.A.
30
N.A.
36.8
Protein Similarity:
100
65.3
98.6
50.4
N.A.
87.2
85.4
N.A.
N.A.
70.4
N.A.
69.5
N.A.
N.A.
45.8
N.A.
55.4
P-Site Identity:
100
93.3
93.3
6.6
N.A.
80
80
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
93.3
93.3
13.3
N.A.
80
80
N.A.
N.A.
0
N.A.
13.3
N.A.
N.A.
33.3
N.A.
33.3
Percent
Protein Identity:
35
36.3
N.A.
30.4
N.A.
N.A.
Protein Similarity:
55
57.7
N.A.
52.7
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
13.3
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
8
8
0
8
31
0
8
0
8
8
24
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
39
0
39
8
24
0
0
8
0
0
0
24
8
% D
% Glu:
8
8
8
0
0
24
0
8
0
0
8
8
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
8
0
0
8
0
0
0
% F
% Gly:
0
47
0
0
16
0
0
8
8
0
0
0
0
0
8
% G
% His:
31
8
0
0
8
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
0
0
8
0
0
8
0
0
% I
% Lys:
0
0
8
0
8
0
0
0
8
0
0
16
16
0
8
% K
% Leu:
8
8
0
0
0
0
8
8
16
39
0
8
39
0
0
% L
% Met:
8
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
8
0
0
8
0
16
0
8
8
24
54
39
8
47
47
% P
% Gln:
0
8
8
8
0
0
8
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
8
16
16
0
31
39
0
8
0
8
8
8
% R
% Ser:
0
8
8
8
16
0
16
24
0
8
0
8
0
16
0
% S
% Thr:
0
8
0
8
0
8
0
8
0
8
0
8
0
0
0
% T
% Val:
0
0
16
0
0
16
0
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
39
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
8
0
0
0
8
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _