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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREG1
All Species:
24.55
Human Site:
S90
Identified Species:
45
UniProt:
O75629
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75629
NP_003842.1
220
24075
S90
R
P
F
A
D
V
L
S
L
S
D
G
P
P
G
Chimpanzee
Pan troglodytes
XP_001157266
335
36715
S205
R
P
F
A
D
V
L
S
L
S
D
G
P
P
G
Rhesus Macaque
Macaca mulatta
XP_001089325
220
24080
S90
R
P
F
A
D
V
L
S
L
S
D
G
P
P
G
Dog
Lupus familis
XP_854297
180
20555
S50
F
G
N
C
L
P
I
S
D
G
P
L
D
N
S
Cat
Felis silvestris
Mouse
Mus musculus
O88668
220
24433
S90
W
P
F
A
D
I
I
S
I
S
D
G
P
P
G
Rat
Rattus norvegicus
NP_001099436
220
24369
S90
R
P
F
A
D
I
I
S
I
S
D
G
P
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJ73
192
21088
S63
F
A
N
I
F
S
I
S
D
G
A
P
G
P
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074159
207
22893
P78
P
G
A
S
S
G
T
P
Y
L
Y
L
T
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624302
290
33697
S121
X
P
A
V
T
L
V
S
Y
T
D
G
L
L
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796937
218
23864
S84
R
S
F
P
A
S
T
S
I
S
D
G
A
L
G
Poplar Tree
Populus trichocarpa
XP_002299070
191
21144
V62
G
A
P
F
G
N
V
V
S
F
S
D
G
L
P
Maize
Zea mays
NP_001148752
210
22772
E81
Y
S
D
G
V
P
G
E
G
R
G
I
P
Y
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_178546
210
23576
P81
V
S
F
S
D
G
L
P
E
K
G
N
G
I
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.7
96.8
32.2
N.A.
76.8
76.8
N.A.
N.A.
55.4
N.A.
50.4
N.A.
N.A.
30
N.A.
36.8
Protein Similarity:
100
65.3
98.6
50.4
N.A.
87.2
85.4
N.A.
N.A.
70.4
N.A.
69.5
N.A.
N.A.
45.8
N.A.
55.4
P-Site Identity:
100
100
100
6.6
N.A.
73.3
80
N.A.
N.A.
20
N.A.
0
N.A.
N.A.
33.3
N.A.
46.6
P-Site Similarity:
100
100
100
13.3
N.A.
93.3
100
N.A.
N.A.
26.6
N.A.
6.6
N.A.
N.A.
53.3
N.A.
53.3
Percent
Protein Identity:
35
36.3
N.A.
30.4
N.A.
N.A.
Protein Similarity:
55
57.7
N.A.
52.7
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
20
N.A.
N.A.
P-Site Similarity:
6.6
6.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
16
39
8
0
0
0
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
47
0
0
0
16
0
54
8
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% E
% Phe:
16
0
54
8
8
0
0
0
0
8
0
0
0
0
8
% F
% Gly:
8
16
0
8
8
16
8
0
8
16
16
54
24
0
62
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
8
0
16
31
0
24
0
0
8
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
0
0
8
8
31
0
24
8
0
16
8
24
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
16
0
0
8
0
0
0
0
0
8
0
8
0
% N
% Pro:
8
47
8
8
0
16
0
16
0
0
8
8
47
47
16
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
39
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
24
0
16
8
16
0
70
8
47
8
0
0
0
8
% S
% Thr:
0
0
0
0
8
0
16
0
0
8
0
0
8
0
0
% T
% Val:
8
0
0
8
8
24
16
8
0
0
0
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
16
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _