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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UPK3A All Species: 10.3
Human Site: S262 Identified Species: 28.33
UniProt: O75631 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75631 NP_008884.1 287 30670 S262 V P K S L G A S E S S Y T S V
Chimpanzee Pan troglodytes XP_515193 284 30395 E260 P K S L G A S E S S Y T S V N
Rhesus Macaque Macaca mulatta XP_001108957 215 22918 E191 P K S L G D S E S S Y T S V N
Dog Lupus familis XP_851414 288 30558 S263 V P R S L G T S E A V Y T S V
Cat Felis silvestris
Mouse Mus musculus Q9JKX8 287 30972 S262 V P K T L G T S E P S Y S S V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511239 231 24873 G207 V S Q E A A P G A S Y S S A S
Chicken Gallus gallus
Frog Xenopus laevis NP_001083096 265 29221 A241 T T A V L Q K A Q E P G D I T
Zebra Danio Brachydanio rerio NP_001093533 276 29951 Y251 L K E H V H P Y D N Q A Y E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FWY9 361 41138 S332 S L L H W S G S G K P W L R L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.5 70 85 N.A. 83.6 N.A. N.A. 43.9 N.A. 37.9 24 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 93.7 71.7 90.2 N.A. 89.9 N.A. N.A. 55 N.A. 55 40 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 73.3 N.A. 73.3 N.A. N.A. 13.3 N.A. 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 20 86.6 N.A. 86.6 N.A. N.A. 33.3 N.A. 20 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 33.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 12 23 12 12 12 12 0 12 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 12 0 0 12 0 0 0 12 0 0 % D
% Glu: 0 0 12 12 0 0 0 23 34 12 0 0 0 12 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 23 34 12 12 12 0 0 12 0 0 0 % G
% His: 0 0 0 23 0 12 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % I
% Lys: 0 34 23 0 0 0 12 0 0 12 0 0 0 0 0 % K
% Leu: 12 12 12 23 45 0 0 0 0 0 0 0 12 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 23 % N
% Pro: 23 34 0 0 0 0 23 0 0 12 23 0 0 0 12 % P
% Gln: 0 0 12 0 0 12 0 0 12 0 12 0 0 0 0 % Q
% Arg: 0 0 12 0 0 0 0 0 0 0 0 0 0 12 0 % R
% Ser: 12 12 23 23 0 12 23 45 23 45 23 12 45 34 12 % S
% Thr: 12 12 0 12 0 0 23 0 0 0 0 23 23 0 12 % T
% Val: 45 0 0 12 12 0 0 0 0 0 12 0 0 23 34 % V
% Trp: 0 0 0 0 12 0 0 0 0 0 0 12 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 12 0 0 34 34 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _