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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINB7
All Species:
4.55
Human Site:
S223
Identified Species:
11.11
UniProt:
O75635
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75635
NP_001035237.1
380
42905
S223
L
S
V
I
E
D
P
S
M
K
I
L
E
L
R
Chimpanzee
Pan troglodytes
XP_523958
392
44073
V233
V
K
E
L
Q
M
Q
V
L
E
L
P
Y
V
N
Rhesus Macaque
Macaca mulatta
XP_001091734
380
42872
S223
L
S
V
I
E
D
P
S
M
K
V
L
E
L
R
Dog
Lupus familis
XP_541072
388
44180
P231
L
S
V
I
R
D
P
P
M
Q
V
L
E
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D695
380
43032
P223
L
S
T
I
Q
Q
P
P
M
Q
V
L
E
L
Q
Rat
Rattus norvegicus
Q4G075
379
42708
P220
K
C
K
V
L
E
M
P
Y
Q
G
G
E
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509117
398
44734
V239
V
E
E
P
Q
L
Q
V
I
E
L
P
Y
V
Q
Chicken
Gallus gallus
P01014
388
43754
K229
T
L
P
A
E
K
M
K
I
L
E
L
P
Y
A
Frog
Xenopus laevis
Q52L45
377
42679
E219
D
I
N
C
R
I
L
E
L
P
Y
V
D
Y
E
Zebra Danio
Brachydanio rerio
NP_001103200
439
48627
P278
N
S
Q
V
L
E
L
P
Y
A
G
K
N
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.8
95.2
80.9
N.A.
73.9
40.2
N.A.
43.4
39.9
38.9
37.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
65.3
97.8
92
N.A.
87.8
61.5
N.A.
64.8
58.5
60.5
57.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
93.3
66.6
N.A.
53.3
13.3
N.A.
0
13.3
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
86.6
N.A.
80
33.3
N.A.
46.6
20
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
10
% A
% Cys:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
30
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
10
20
0
30
20
0
10
0
20
10
0
50
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
20
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
40
0
10
0
0
20
0
10
0
0
0
0
% I
% Lys:
10
10
10
0
0
10
0
10
0
20
0
10
0
0
10
% K
% Leu:
40
10
0
10
20
10
20
0
20
10
20
50
0
60
0
% L
% Met:
0
0
0
0
0
10
20
0
40
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
0
0
0
0
0
0
10
0
10
% N
% Pro:
0
0
10
10
0
0
40
40
0
10
0
20
10
0
0
% P
% Gln:
0
0
10
0
30
10
20
0
0
30
0
0
0
0
20
% Q
% Arg:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
20
% R
% Ser:
0
50
0
0
0
0
0
20
0
0
0
0
0
0
20
% S
% Thr:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
20
0
30
20
0
0
0
20
0
0
30
10
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
20
0
10
0
20
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _