KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OFD1
All Species:
21.21
Human Site:
S435
Identified Species:
66.67
UniProt:
O75665
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75665
NP_003602.1
1012
116671
S435
N
E
K
V
K
E
M
S
D
Y
S
L
L
K
E
Chimpanzee
Pan troglodytes
XP_517799
1005
116295
S435
N
E
K
V
K
V
M
S
D
Y
S
L
L
K
E
Rhesus Macaque
Macaca mulatta
XP_001098347
1013
116995
S435
N
E
K
V
K
E
M
S
D
Y
S
L
L
K
E
Dog
Lupus familis
XP_537958
991
114088
S423
N
E
K
V
K
E
M
S
D
Y
S
L
L
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80Z25
1017
117327
S435
N
E
K
V
R
E
M
S
D
Y
S
Q
L
K
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515341
1086
125182
T437
T
E
K
L
R
E
T
T
D
Y
P
L
L
K
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1RM03
499
62332
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783748
861
98372
E354
T
Y
E
N
R
L
K
E
E
T
K
R
Y
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.4
96
73.3
N.A.
66.8
N.A.
N.A.
53.4
N.A.
N.A.
20.8
N.A.
N.A.
N.A.
N.A.
26
Protein Similarity:
100
93.5
97.5
83.5
N.A.
79.6
N.A.
N.A.
68.1
N.A.
N.A.
34.1
N.A.
N.A.
N.A.
N.A.
46.8
P-Site Identity:
100
93.3
100
100
N.A.
86.6
N.A.
N.A.
60
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
100
100
N.A.
93.3
N.A.
N.A.
80
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% D
% Glu:
0
75
13
0
0
63
0
13
13
0
0
0
0
13
75
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
75
0
50
0
13
0
0
0
13
0
0
75
0
% K
% Leu:
0
0
0
13
0
13
0
0
0
0
0
63
75
0
13
% L
% Met:
0
0
0
0
0
0
63
0
0
0
0
0
0
0
0
% M
% Asn:
63
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% Q
% Arg:
0
0
0
0
38
0
0
0
0
0
0
13
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
63
0
0
63
0
0
0
0
% S
% Thr:
25
0
0
0
0
0
13
13
0
13
0
0
0
0
0
% T
% Val:
0
0
0
63
0
13
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
13
0
0
0
0
0
0
0
75
0
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _