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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OFD1 All Species: 14.55
Human Site: T990 Identified Species: 45.71
UniProt: O75665 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75665 NP_003602.1 1012 116671 T990 Q E G S L V D T L Q S S D K V
Chimpanzee Pan troglodytes XP_517799 1005 116295 T983 Q E G S L V D T L Q C S D K V
Rhesus Macaque Macaca mulatta XP_001098347 1013 116995 T991 Q E G S L V D T L Q S S D K V
Dog Lupus familis XP_537958 991 114088 T969 R E G S E V D T L P S S D K D
Cat Felis silvestris
Mouse Mus musculus Q80Z25 1017 117327 M995 K E C S L V D M M M P S D K D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515341 1086 125182 E1005 N S K K E V E E T S I M E T L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1RM03 499 62332 T478 E E E L R L E T D R M I R Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783748 861 98372 G840 L N T S D L G G P D R K D D A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.4 96 73.3 N.A. 66.8 N.A. N.A. 53.4 N.A. N.A. 20.8 N.A. N.A. N.A. N.A. 26
Protein Similarity: 100 93.5 97.5 83.5 N.A. 79.6 N.A. N.A. 68.1 N.A. N.A. 34.1 N.A. N.A. N.A. N.A. 46.8
P-Site Identity: 100 93.3 100 73.3 N.A. 53.3 N.A. N.A. 6.6 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 93.3 100 80 N.A. 66.6 N.A. N.A. 26.6 N.A. N.A. 46.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % A
% Cys: 0 0 13 0 0 0 0 0 0 0 13 0 0 0 0 % C
% Asp: 0 0 0 0 13 0 63 0 13 13 0 0 75 13 25 % D
% Glu: 13 75 13 0 25 0 25 13 0 0 0 0 13 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 50 0 0 0 13 13 0 0 0 0 0 0 13 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 13 13 0 0 0 % I
% Lys: 13 0 13 13 0 0 0 0 0 0 0 13 0 63 0 % K
% Leu: 13 0 0 13 50 25 0 0 50 0 0 0 0 0 13 % L
% Met: 0 0 0 0 0 0 0 13 13 13 13 13 0 0 0 % M
% Asn: 13 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 13 13 13 0 0 0 0 % P
% Gln: 38 0 0 0 0 0 0 0 0 38 0 0 0 13 0 % Q
% Arg: 13 0 0 0 13 0 0 0 0 13 13 0 13 0 0 % R
% Ser: 0 13 0 75 0 0 0 0 0 13 38 63 0 0 0 % S
% Thr: 0 0 13 0 0 0 0 63 13 0 0 0 0 13 0 % T
% Val: 0 0 0 0 0 75 0 0 0 0 0 0 0 0 38 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _