KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA4
All Species:
21.52
Human Site:
S324
Identified Species:
31.56
UniProt:
O75676
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75676
NP_001006945.1
772
85606
S324
P
F
R
P
Q
I
R
S
E
L
D
V
G
N
F
Chimpanzee
Pan troglodytes
XP_508900
901
98668
S453
P
F
R
P
Q
I
R
S
E
L
D
V
G
N
F
Rhesus Macaque
Macaca mulatta
XP_001114877
772
85557
S324
P
F
R
P
Q
I
R
S
E
L
D
V
G
N
F
Dog
Lupus familis
XP_854926
772
85603
S324
P
F
R
P
Q
I
R
S
E
L
D
V
G
N
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
S324
P
F
R
P
Q
I
R
S
E
L
D
V
G
N
F
Rat
Rattus norvegicus
Q63531
735
82865
R304
F
K
R
N
P
A
N
R
L
G
S
G
P
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
N264
R
D
E
L
D
V
S
N
F
A
E
E
F
T
E
Chicken
Gallus gallus
Q5F3L1
789
89022
D331
P
F
K
P
V
I
R
D
E
L
D
V
S
N
F
Frog
Xenopus laevis
P10665
733
82620
S307
N
P
T
N
R
L
G
S
A
M
E
G
A
E
E
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
N308
L
F
K
R
N
P
S
N
R
L
G
A
G
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
T540
I
N
W
Q
E
L
R
T
K
R
R
K
A
P
Y
Honey Bee
Apis mellifera
XP_395099
910
102507
H363
P
F
V
P
Q
I
A
H
E
L
D
T
S
N
F
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
K282
V
D
E
I
K
N
H
K
F
M
S
S
I
D
W
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
G299
P
F
R
P
H
I
N
G
E
L
D
T
S
N
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
P47
Q
F
S
D
V
F
G
P
M
P
E
A
N
S
E
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
I255
K
I
D
V
F
A
R
I
P
S
L
L
L
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
98.6
96.7
N.A.
95.8
41.3
N.A.
56
64
41
41.9
N.A.
27
45.1
48.1
48.2
Protein Similarity:
100
85.6
98.9
98
N.A.
96.7
60.6
N.A.
71.6
78.4
59
60.3
N.A.
38.9
60.1
64.3
61.8
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
0
73.3
6.6
20
N.A.
6.6
66.6
0
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
20
80
33.3
33.3
N.A.
40
66.6
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
13
7
0
7
7
0
13
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
7
7
7
0
0
7
0
0
50
0
0
13
7
% D
% Glu:
0
0
13
0
7
0
0
0
50
0
19
7
0
7
19
% E
% Phe:
7
63
0
0
7
7
0
0
13
0
0
0
7
0
50
% F
% Gly:
0
0
0
0
0
0
13
7
0
7
7
13
38
0
7
% G
% His:
0
0
0
0
7
0
7
7
0
0
0
0
0
0
0
% H
% Ile:
7
7
0
7
0
50
0
7
0
0
0
0
7
0
0
% I
% Lys:
7
7
13
0
7
0
0
7
7
0
0
7
0
0
0
% K
% Leu:
7
0
0
7
0
13
0
0
7
57
7
7
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
13
0
0
0
0
0
% M
% Asn:
7
7
0
13
7
7
13
13
0
0
0
0
7
50
0
% N
% Pro:
50
7
0
50
7
7
0
7
7
7
0
0
7
19
0
% P
% Gln:
7
0
0
7
38
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
44
7
7
0
50
7
7
7
7
0
0
0
0
% R
% Ser:
0
0
7
0
0
0
13
38
0
7
13
7
19
7
7
% S
% Thr:
0
0
7
0
0
0
0
7
0
0
0
13
0
7
0
% T
% Val:
7
0
7
7
13
7
0
0
0
0
0
38
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _