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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPS6KA4 All Species: 23.64
Human Site: S360 Identified Species: 34.67
UniProt: O75676 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75676 NP_001006945.1 772 85606 S360 P R I F Q G Y S F V A P S I L
Chimpanzee Pan troglodytes XP_508900 901 98668 S489 P R I F Q G Y S F V A P S I L
Rhesus Macaque Macaca mulatta XP_001114877 772 85557 S360 P R I F Q G Y S F V A P S I L
Dog Lupus familis XP_854926 772 85603 S360 P R I F Q G Y S F V A P S I L
Cat Felis silvestris
Mouse Mus musculus Q9Z2B9 773 85721 S360 P R I F Q G Y S F V A P S I L
Rat Rattus norvegicus Q63531 735 82865 P340 E I K P P F K P A V A Q P D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506738 716 80894 L300 S F V A P S I L F K R N A A I
Chicken Gallus gallus Q5F3L1 789 89022 F367 K I F Q G Y S F V A P S I L F
Frog Xenopus laevis P10665 733 82620 T343 P P F K P A V T Q A D D T Y Y
Zebra Danio Brachydanio rerio Q6PFQ0 740 83378 K344 R E L Q P P F K P A S G K P D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3I5 1207 137026 A576 P E D P E C D A P P S R I R L
Honey Bee Apis mellifera XP_395099 910 102507 Y399 K I F R G Y S Y V A P S I L F
Nematode Worm Caenorhab. elegans Q18846 772 87050 F318 T Q F F S A E F T S Q P P L Y
Sea Urchin Strong. purpuratus XP_786494 918 102561 S335 A R V F R G Y S F I A P S I L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39030 471 53019 H83 G P S L V V S H S L K M N K L
Baker's Yeast Sacchar. cerevisiae P18961 677 76646 L291 N T N Q D I H L D S F H L P L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.4 98.6 96.7 N.A. 95.8 41.3 N.A. 56 64 41 41.9 N.A. 27 45.1 48.1 48.2
Protein Similarity: 100 85.6 98.9 98 N.A. 96.7 60.6 N.A. 71.6 78.4 59 60.3 N.A. 38.9 60.1 64.3 61.8
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. 6.6 0 6.6 0 N.A. 13.3 0 13.3 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 26.6 6.6 20 20 N.A. 33.3 6.6 26.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 20.4 21.2 N.A.
Protein Similarity: N.A. N.A. N.A. 35.6 37.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 0 13 0 7 7 25 44 0 7 7 0 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 7 0 7 0 7 0 7 7 0 7 13 % D
% Glu: 7 13 0 0 7 0 7 0 0 0 0 0 0 0 0 % E
% Phe: 0 7 25 44 0 7 7 13 44 0 7 0 0 0 13 % F
% Gly: 7 0 0 0 13 38 0 0 0 0 0 7 0 0 0 % G
% His: 0 0 0 0 0 0 7 7 0 0 0 7 0 0 0 % H
% Ile: 0 19 32 0 0 7 7 0 0 7 0 0 19 38 7 % I
% Lys: 13 0 7 7 0 0 7 7 0 7 7 0 7 7 0 % K
% Leu: 0 0 7 7 0 0 0 13 0 7 0 0 7 19 57 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 7 0 7 0 0 0 0 0 0 0 0 7 7 0 0 % N
% Pro: 44 13 0 13 25 7 0 7 13 7 13 44 13 13 0 % P
% Gln: 0 7 0 19 32 0 0 0 7 0 7 7 0 0 0 % Q
% Arg: 7 38 0 7 7 0 0 0 0 0 7 7 0 7 0 % R
% Ser: 7 0 7 0 7 7 19 38 7 13 13 13 38 0 0 % S
% Thr: 7 7 0 0 0 0 0 7 7 0 0 0 7 0 0 % T
% Val: 0 0 13 0 7 7 7 0 13 38 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 13 38 7 0 0 0 0 0 7 13 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _