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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA4
All Species:
32.12
Human Site:
S634
Identified Species:
47.11
UniProt:
O75676
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75676
NP_001006945.1
772
85606
S634
K
I
R
E
G
R
F
S
L
D
G
E
A
W
Q
Chimpanzee
Pan troglodytes
XP_508900
901
98668
S763
K
I
R
E
G
R
F
S
L
D
G
E
A
W
Q
Rhesus Macaque
Macaca mulatta
XP_001114877
772
85557
S634
K
I
R
E
G
R
F
S
L
D
G
E
A
W
Q
Dog
Lupus familis
XP_854926
772
85603
S635
K
I
R
E
G
R
F
S
L
D
G
E
A
W
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
S634
K
I
R
E
G
R
F
S
L
D
G
E
A
W
Q
Rat
Rattus norvegicus
Q63531
735
82865
D596
Q
G
Y
D
E
G
C
D
I
W
S
L
G
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
S564
K
I
K
K
G
D
F
S
F
E
G
E
A
W
K
Chicken
Gallus gallus
Q5F3L1
789
89022
S637
K
I
K
K
G
E
F
S
F
E
G
E
A
W
K
Frog
Xenopus laevis
P10665
733
82620
D594
Q
G
Y
D
E
G
C
D
I
W
S
L
G
I
L
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
L605
D
I
W
S
L
G
V
L
L
Y
T
M
L
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
N846
R
M
R
R
G
T
F
N
Q
R
S
M
R
W
E
Honey Bee
Apis mellifera
XP_395099
910
102507
H666
F
D
S
E
S
W
S
H
V
S
N
L
A
R
Q
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
S613
R
I
C
R
A
E
F
S
F
T
G
D
A
W
T
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
S607
R
I
K
H
G
N
F
S
F
D
G
E
E
W
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
P336
E
M
L
T
G
K
P
P
F
L
G
S
K
G
K
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
Y542
M
M
T
G
L
P
P
Y
Y
D
E
N
V
P
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
98.6
96.7
N.A.
95.8
41.3
N.A.
56
64
41
41.9
N.A.
27
45.1
48.1
48.2
Protein Similarity:
100
85.6
98.9
98
N.A.
96.7
60.6
N.A.
71.6
78.4
59
60.3
N.A.
38.9
60.1
64.3
61.8
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
60
60
0
13.3
N.A.
26.6
20
40
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
86.6
86.6
20
13.3
N.A.
53.3
26.6
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
0
0
0
0
57
7
0
% A
% Cys:
0
0
7
0
0
0
13
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
13
0
7
0
13
0
44
0
7
0
0
0
% D
% Glu:
7
0
0
38
13
13
0
0
0
13
7
50
7
0
7
% E
% Phe:
7
0
0
0
0
0
63
0
32
0
0
0
0
0
0
% F
% Gly:
0
13
0
7
63
19
0
0
0
0
63
0
13
7
7
% G
% His:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
63
0
0
0
0
0
0
13
0
0
0
0
7
0
% I
% Lys:
44
0
19
13
0
7
0
0
0
0
0
0
7
0
19
% K
% Leu:
0
0
7
0
13
0
0
7
38
7
0
19
7
0
13
% L
% Met:
7
19
0
0
0
0
0
0
0
0
0
13
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
7
0
0
7
7
0
0
7
% N
% Pro:
0
0
0
0
0
7
13
7
0
0
0
0
0
7
0
% P
% Gln:
13
0
0
0
0
0
0
0
7
0
0
0
0
0
38
% Q
% Arg:
19
0
38
13
0
32
0
0
0
7
0
0
7
7
0
% R
% Ser:
0
0
7
7
7
0
7
57
0
7
19
7
0
0
0
% S
% Thr:
0
0
7
7
0
7
0
0
0
7
7
0
0
0
7
% T
% Val:
0
0
0
0
0
0
7
0
7
0
0
0
7
7
7
% V
% Trp:
0
0
7
0
0
7
0
0
0
13
0
0
0
63
0
% W
% Tyr:
0
0
13
0
0
0
0
7
7
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _