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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA4
All Species:
20.61
Human Site:
S671
Identified Species:
30.22
UniProt:
O75676
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75676
NP_001006945.1
772
85606
S671
K
L
E
G
L
R
G
S
S
W
L
Q
D
G
S
Chimpanzee
Pan troglodytes
XP_508900
901
98668
S800
K
L
E
G
L
R
G
S
S
W
L
Q
D
G
S
Rhesus Macaque
Macaca mulatta
XP_001114877
772
85557
S671
K
L
E
G
L
R
D
S
S
W
L
Q
D
G
S
Dog
Lupus familis
XP_854926
772
85603
S672
K
L
E
G
L
R
G
S
S
W
L
Q
D
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
S671
K
L
E
G
L
R
S
S
S
W
L
Q
D
G
S
Rat
Rattus norvegicus
Q63531
735
82865
K633
L
T
R
I
S
S
G
K
F
T
L
S
G
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
N601
K
M
S
G
L
R
Y
N
E
W
L
Q
D
G
S
Chicken
Gallus gallus
Q5F3L1
789
89022
N674
K
M
S
S
L
R
Y
N
E
W
L
Q
D
G
S
Frog
Xenopus laevis
P10665
733
82620
K631
L
A
R
I
G
S
G
K
F
T
L
R
G
G
N
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
N642
K
F
S
L
S
G
G
N
W
D
S
V
S
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
S883
T
L
S
D
I
L
D
S
E
W
L
Q
Y
G
S
Honey Bee
Apis mellifera
XP_395099
910
102507
S703
P
W
L
Q
E
S
N
S
F
D
V
A
S
S
Y
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
H650
S
M
Q
E
L
T
A
H
M
W
L
K
S
S
A
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
N644
T
T
D
D
L
L
Q
N
E
W
I
Q
G
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
K373
L
L
K
G
L
L
Q
K
E
P
E
R
R
L
G
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
R579
L
L
I
G
L
L
S
R
D
P
S
R
R
L
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
98.6
96.7
N.A.
95.8
41.3
N.A.
56
64
41
41.9
N.A.
27
45.1
48.1
48.2
Protein Similarity:
100
85.6
98.9
98
N.A.
96.7
60.6
N.A.
71.6
78.4
59
60.3
N.A.
38.9
60.1
64.3
61.8
P-Site Identity:
100
100
93.3
100
N.A.
93.3
20
N.A.
66.6
60
20
20
N.A.
46.6
6.6
20
20
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
26.6
N.A.
80
73.3
33.3
26.6
N.A.
53.3
13.3
46.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
7
0
0
0
0
7
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
13
0
0
13
0
7
13
0
0
44
7
0
% D
% Glu:
0
0
32
7
7
0
0
0
32
0
7
0
0
0
0
% E
% Phe:
0
7
0
0
0
0
0
0
19
0
0
0
0
0
0
% F
% Gly:
0
0
0
50
7
7
38
0
0
0
0
0
19
63
13
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
13
7
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
50
0
7
0
0
0
0
19
0
0
0
7
0
0
0
% K
% Leu:
25
50
7
7
69
25
0
0
0
0
69
0
0
13
0
% L
% Met:
0
19
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
25
0
0
0
0
0
0
13
% N
% Pro:
7
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% P
% Gln:
0
0
7
7
0
0
13
0
0
0
0
57
0
7
7
% Q
% Arg:
0
0
13
0
0
44
0
7
0
0
0
19
13
0
0
% R
% Ser:
7
0
25
7
13
19
13
44
32
0
13
7
19
13
57
% S
% Thr:
13
13
0
0
0
7
0
0
0
13
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
7
63
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
13
0
0
0
0
0
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _