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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPS6KA4 All Species: 30.91
Human Site: S682 Identified Species: 45.33
UniProt: O75676 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75676 NP_001006945.1 772 85606 S682 Q D G S A R S S P P L R T P D
Chimpanzee Pan troglodytes XP_508900 901 98668 S811 Q D G S A R S S P P L R T P D
Rhesus Macaque Macaca mulatta XP_001114877 772 85557 S682 Q D G S A R S S P P L R T P D
Dog Lupus familis XP_854926 772 85603 S683 Q D G S A R S S P P L R T P D
Cat Felis silvestris
Mouse Mus musculus Q9Z2B9 773 85721 S682 Q D G S A R S S P P L R T P D
Rat Rattus norvegicus Q63531 735 82865 V644 S G G N W N T V S E T A K D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506738 716 80894 S612 Q D G S Q L S S N P L M T P D
Chicken Gallus gallus Q5F3L1 789 89022 S685 Q D G S Q L S S N P L M T P D
Frog Xenopus laevis P10665 733 82620 V642 R G G N W N T V S A A A K D L
Zebra Danio Brachydanio rerio Q6PFQ0 740 83378 L653 V S D S S K D L L S H M L H V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3I5 1207 137026 D894 Q Y G S N D P D V D I I L P Q
Honey Bee Apis mellifera XP_395099 910 102507 V714 A S S Y D V N V L D N S G S N
Nematode Worm Caenorhab. elegans Q18846 772 87050 T661 K S S A S M D T P L Q T P S I
Sea Urchin Strong. purpuratus XP_786494 918 102561 S655 Q G Q Q L S T S T P L M T P D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39030 471 53019 S384 R R L G S G P S G A E E I K K
Baker's Yeast Sacchar. cerevisiae P18961 677 76646 T590 R R L G V N G T D E I R N H P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.4 98.6 96.7 N.A. 95.8 41.3 N.A. 56 64 41 41.9 N.A. 27 45.1 48.1 48.2
Protein Similarity: 100 85.6 98.9 98 N.A. 96.7 60.6 N.A. 71.6 78.4 59 60.3 N.A. 38.9 60.1 64.3 61.8
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 73.3 73.3 6.6 6.6 N.A. 26.6 0 6.6 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 73.3 73.3 26.6 20 N.A. 33.3 13.3 33.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. 20.4 21.2 N.A.
Protein Similarity: N.A. N.A. N.A. 35.6 37.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 32 0 0 0 0 13 7 13 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 44 7 0 7 7 13 7 7 13 0 0 0 13 50 % D
% Glu: 0 0 0 0 0 0 0 0 0 13 7 7 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 19 63 13 0 7 7 0 7 0 0 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 0 13 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 13 7 7 0 7 % I
% Lys: 7 0 0 0 0 7 0 0 0 0 0 0 13 7 7 % K
% Leu: 0 0 13 0 7 13 0 7 13 7 50 0 13 0 13 % L
% Met: 0 0 0 0 0 7 0 0 0 0 0 25 0 0 0 % M
% Asn: 0 0 0 13 7 19 7 0 13 0 7 0 7 0 7 % N
% Pro: 0 0 0 0 0 0 13 0 38 50 0 0 7 57 7 % P
% Gln: 57 0 7 7 13 0 0 0 0 0 7 0 0 0 7 % Q
% Arg: 19 13 0 0 0 32 0 0 0 0 0 38 0 0 0 % R
% Ser: 7 19 13 57 19 7 44 57 13 7 0 7 0 13 0 % S
% Thr: 0 0 0 0 0 0 19 13 7 0 7 7 50 0 0 % T
% Val: 7 0 0 0 7 7 0 19 7 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _