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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA4
All Species:
27.58
Human Site:
T687
Identified Species:
40.44
UniProt:
O75676
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75676
NP_001006945.1
772
85606
T687
R
S
S
P
P
L
R
T
P
D
V
L
E
S
S
Chimpanzee
Pan troglodytes
XP_508900
901
98668
T816
R
S
S
P
P
L
R
T
P
D
V
L
E
S
S
Rhesus Macaque
Macaca mulatta
XP_001114877
772
85557
T687
R
S
S
P
P
L
R
T
P
D
V
L
E
S
S
Dog
Lupus familis
XP_854926
772
85603
T688
R
S
S
P
P
L
R
T
P
D
V
L
E
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
T687
R
S
S
P
P
L
R
T
P
D
V
L
E
S
S
Rat
Rattus norvegicus
Q63531
735
82865
K649
N
T
V
S
E
T
A
K
D
L
V
S
K
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
T617
L
S
S
N
P
L
M
T
P
D
I
L
G
S
S
Chicken
Gallus gallus
Q5F3L1
789
89022
T690
L
S
S
N
P
L
M
T
P
D
N
L
G
S
S
Frog
Xenopus laevis
P10665
733
82620
K647
N
T
V
S
A
A
A
K
D
L
V
S
R
M
L
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
L658
K
D
L
L
S
H
M
L
H
V
D
P
H
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
L899
D
P
D
V
D
I
I
L
P
Q
Q
M
V
V
D
Honey Bee
Apis mellifera
XP_395099
910
102507
G719
V
N
V
L
D
N
S
G
S
N
A
L
L
E
K
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
P666
M
D
T
P
L
Q
T
P
S
I
L
P
S
S
A
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
T660
S
T
S
T
P
L
M
T
P
D
I
L
N
S
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
I389
G
P
S
G
A
E
E
I
K
K
H
K
W
F
K
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
N595
N
G
T
D
E
I
R
N
H
P
F
F
K
D
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
98.6
96.7
N.A.
95.8
41.3
N.A.
56
64
41
41.9
N.A.
27
45.1
48.1
48.2
Protein Similarity:
100
85.6
98.9
98
N.A.
96.7
60.6
N.A.
71.6
78.4
59
60.3
N.A.
38.9
60.1
64.3
61.8
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
66.6
66.6
6.6
0
N.A.
6.6
6.6
13.3
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
73.3
66.6
13.3
6.6
N.A.
20
20
33.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
7
13
0
0
0
7
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
7
13
7
7
13
0
0
0
13
50
7
0
0
7
7
% D
% Glu:
0
0
0
0
13
7
7
0
0
0
0
0
32
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
7
0
7
0
% F
% Gly:
7
7
0
7
0
0
0
7
0
0
0
0
13
0
0
% G
% His:
0
0
0
0
0
7
0
0
13
0
7
0
7
7
0
% H
% Ile:
0
0
0
0
0
13
7
7
0
7
13
0
0
0
7
% I
% Lys:
7
0
0
0
0
0
0
13
7
7
0
7
13
0
13
% K
% Leu:
13
0
7
13
7
50
0
13
0
13
7
57
7
0
13
% L
% Met:
7
0
0
0
0
0
25
0
0
0
0
7
0
13
0
% M
% Asn:
19
7
0
13
0
7
0
7
0
7
7
0
7
0
0
% N
% Pro:
0
13
0
38
50
0
0
7
57
7
0
13
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
7
7
0
0
0
0
% Q
% Arg:
32
0
0
0
0
0
38
0
0
0
0
0
7
0
7
% R
% Ser:
7
44
57
13
7
0
7
0
13
0
0
13
7
57
44
% S
% Thr:
0
19
13
7
0
7
7
50
0
0
0
0
0
0
0
% T
% Val:
7
0
19
7
0
0
0
0
0
7
44
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _