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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA4
All Species:
24.24
Human Site:
T705
Identified Species:
35.56
UniProt:
O75676
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75676
NP_001006945.1
772
85606
T705
V
R
S
G
L
N
A
T
F
M
A
F
N
R
G
Chimpanzee
Pan troglodytes
XP_508900
901
98668
T834
V
R
S
G
L
N
A
T
F
M
A
F
N
R
G
Rhesus Macaque
Macaca mulatta
XP_001114877
772
85557
T705
V
R
S
G
L
N
A
T
F
M
A
F
N
R
G
Dog
Lupus familis
XP_854926
772
85603
T706
V
R
S
G
L
N
A
T
F
M
A
F
N
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
T705
V
R
S
G
L
N
A
T
F
M
A
F
N
R
G
Rat
Rattus norvegicus
Q63531
735
82865
K667
P
H
Q
R
L
T
A
K
Q
V
L
Q
H
P
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
T635
V
H
T
C
V
K
A
T
F
H
A
F
N
K
Y
Chicken
Gallus gallus
Q5F3L1
789
89022
T708
V
H
T
Y
V
K
A
T
F
H
A
F
N
K
Y
Frog
Xenopus laevis
P10665
733
82620
K665
P
H
K
R
L
T
A
K
Q
V
L
Q
H
E
W
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
W676
E
Q
V
L
K
H
S
W
I
A
C
R
D
Q
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
G917
D
T
M
E
Q
P
T
G
G
M
F
D
D
Q
Q
Honey Bee
Apis mellifera
XP_395099
910
102507
G737
F
R
L
R
E
V
D
G
A
R
L
A
Q
R
R
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
F684
F
N
E
T
L
R
A
F
L
H
A
N
R
D
G
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
M678
Q
K
R
V
K
A
T
M
R
A
F
H
T
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
E407
W
K
K
L
E
A
R
E
V
Q
P
S
F
K
P
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
I613
K
L
L
L
K
G
Y
I
P
P
Y
K
P
I
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
98.6
96.7
N.A.
95.8
41.3
N.A.
56
64
41
41.9
N.A.
27
45.1
48.1
48.2
Protein Similarity:
100
85.6
98.9
98
N.A.
96.7
60.6
N.A.
71.6
78.4
59
60.3
N.A.
38.9
60.1
64.3
61.8
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
46.6
46.6
13.3
0
N.A.
6.6
13.3
26.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
66.6
66.6
26.6
33.3
N.A.
20
13.3
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
13
63
0
7
13
50
7
0
7
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
7
0
0
0
0
7
13
7
0
% D
% Glu:
7
0
7
7
13
0
0
7
0
0
0
0
0
7
0
% E
% Phe:
13
0
0
0
0
0
0
7
44
0
13
44
7
0
0
% F
% Gly:
0
0
0
32
0
7
0
13
7
0
0
0
0
0
38
% G
% His:
0
25
0
0
0
7
0
0
0
19
0
7
13
0
0
% H
% Ile:
0
0
0
0
0
0
0
7
7
0
0
0
0
7
0
% I
% Lys:
7
13
13
0
19
13
0
13
0
0
0
7
0
19
0
% K
% Leu:
0
7
13
19
50
0
0
0
7
0
19
0
0
0
0
% L
% Met:
0
0
7
0
0
0
0
7
0
38
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
32
0
0
0
0
0
7
44
0
7
% N
% Pro:
13
0
0
0
0
7
0
0
7
7
7
0
7
7
7
% P
% Gln:
7
7
7
0
7
0
0
0
13
7
0
13
7
13
13
% Q
% Arg:
0
38
7
19
0
7
7
0
7
7
0
7
7
38
7
% R
% Ser:
0
0
32
0
0
0
7
0
0
0
0
7
0
0
0
% S
% Thr:
0
7
13
7
0
13
13
44
0
0
0
0
7
0
0
% T
% Val:
44
0
7
7
13
7
0
0
7
13
0
0
0
0
7
% V
% Trp:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
13
% W
% Tyr:
0
0
0
7
0
0
7
0
0
0
7
0
0
0
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _