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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPS6KA4 All Species: 21.82
Human Site: Y342 Identified Species: 32
UniProt: O75676 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75676 NP_001006945.1 772 85606 Y342 F T R L E P V Y S P P G S P P
Chimpanzee Pan troglodytes XP_508900 901 98668 Y471 F T R L E P V Y S P P G S P P
Rhesus Macaque Macaca mulatta XP_001114877 772 85557 Y342 F T R L E P V Y S P P G S P P
Dog Lupus familis XP_854926 772 85603 Y342 F T R L E P V Y S P P G S P P
Cat Felis silvestris
Mouse Mus musculus Q9Z2B9 773 85721 Y342 F T R L E P V Y S P A G S P P
Rat Rattus norvegicus Q63531 735 82865 S322 I K R H I F Y S T I D W N K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506738 716 80894 P282 T Y S P A A L P Q S S E R I F
Chicken Gallus gallus Q5F3L1 789 89022 Y349 F T E M D P T Y S P A A T P Q
Frog Xenopus laevis P10665 733 82620 D325 Q P F F S T I D W N K L F R R
Zebra Danio Brachydanio rerio Q6PFQ0 740 83378 F326 E I K R H T F F S T I D W N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3I5 1207 137026 Q558 L T A E D D V Q N F S N E F T
Honey Bee Apis mellifera XP_395099 910 102507 D381 F T K M I A A D S P A V V P P
Nematode Worm Caenorhab. elegans Q18846 772 87050 V300 V K R T L K P V I V P R I G H
Sea Urchin Strong. purpuratus XP_786494 918 102561 D317 F T S L V P A D S P A D I P K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39030 471 53019 A65 D V A Y D E P A V V Y S R S H
Baker's Yeast Sacchar. cerevisiae P18961 677 76646 D273 Q Q E I G E Q D E V L K E I L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.4 98.6 96.7 N.A. 95.8 41.3 N.A. 56 64 41 41.9 N.A. 27 45.1 48.1 48.2
Protein Similarity: 100 85.6 98.9 98 N.A. 96.7 60.6 N.A. 71.6 78.4 59 60.3 N.A. 38.9 60.1 64.3 61.8
P-Site Identity: 100 100 100 100 N.A. 93.3 6.6 N.A. 0 46.6 0 6.6 N.A. 13.3 40 13.3 46.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 20 N.A. 6.6 66.6 6.6 20 N.A. 26.6 53.3 13.3 46.6
Percent
Protein Identity: N.A. N.A. N.A. 20.4 21.2 N.A.
Protein Similarity: N.A. N.A. N.A. 35.6 37.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 0 7 13 13 7 0 0 25 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 19 7 0 25 0 0 7 13 0 0 0 % D
% Glu: 7 0 13 7 32 13 0 0 7 0 0 7 13 0 0 % E
% Phe: 50 0 7 7 0 7 7 7 0 7 0 0 7 7 7 % F
% Gly: 0 0 0 0 7 0 0 0 0 0 0 32 0 7 0 % G
% His: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 13 % H
% Ile: 7 7 0 7 13 0 7 0 7 7 7 0 13 13 0 % I
% Lys: 0 13 13 0 0 7 0 0 0 0 7 7 0 7 13 % K
% Leu: 7 0 0 38 7 0 7 0 0 0 7 7 0 0 13 % L
% Met: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 7 0 7 7 7 0 % N
% Pro: 0 7 0 7 0 44 13 7 0 50 32 0 0 50 38 % P
% Gln: 13 7 0 0 0 0 7 7 7 0 0 0 0 0 7 % Q
% Arg: 0 0 44 7 0 0 0 0 0 0 0 7 13 7 7 % R
% Ser: 0 0 13 0 7 0 0 7 57 7 13 7 32 7 0 % S
% Thr: 7 57 0 7 0 13 7 0 7 7 0 0 7 0 7 % T
% Val: 7 7 0 0 7 0 38 7 7 19 0 7 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 7 7 0 0 % W
% Tyr: 0 7 0 7 0 0 7 38 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _