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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SURF6 All Species: 10.3
Human Site: S22 Identified Species: 17.44
UniProt: O75683 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75683 NP_006744.2 361 41450 S22 A K K I C S H S A P E Q Q A R
Chimpanzee Pan troglodytes XP_001169391 361 41388 S22 A K K I C S H S G P E Q Q A R
Rhesus Macaque Macaca mulatta XP_001101299 361 41311 S22 A K K I C S H S G P E Q Q A R
Dog Lupus familis XP_849838 514 57534 P183 A R K I C S Q P S L E P Q K R
Cat Felis silvestris
Mouse Mus musculus P70279 355 41216 P22 A K K I C A Q P G P E R Q R S
Rat Rattus norvegicus NP_001015014 354 40813 P22 A K K I C A Q P G P E R Q R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514709 169 20180
Chicken Gallus gallus NP_001025853 356 41570 K22 A R K V C A Q K A P E S R K R
Frog Xenopus laevis Q9I8B0 341 39883 P22 A K K V C T Q P S Q E P R K R
Zebra Danio Brachydanio rerio NP_957359 362 41602 H22 T R K V C V S H K Q E P K K R
Tiger Blowfish Takifugu rubipres O57594 359 41402 E24 V I S Q P D Q E R K K K Q F A
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q23525 472 54243 D122 K E K V V K K D Q K K Q D K K
Sea Urchin Strong. purpuratus XP_780432 428 48512 Y30 T D L I P A R Y Y F E Q E T K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36080 434 50463 E31 P A K Y Y Y D E K S Q E Q W K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.4 48 N.A. 72.5 73.1 N.A. 34.3 49.3 49.8 44.4 45.4 N.A. N.A. 21.1 25.2
Protein Similarity: 100 99.4 97.7 58.3 N.A. 82.2 83.6 N.A. 42.6 70 68.9 67.6 67 N.A. N.A. 38.9 51.6
P-Site Identity: 100 93.3 93.3 53.3 N.A. 53.3 53.3 N.A. 0 46.6 40 26.6 6.6 N.A. N.A. 13.3 20
P-Site Similarity: 100 93.3 93.3 66.6 N.A. 66.6 66.6 N.A. 0 73.3 66.6 46.6 20 N.A. N.A. 40 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 58 8 0 0 0 29 0 0 15 0 0 0 0 22 8 % A
% Cys: 0 0 0 0 65 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 8 8 8 0 0 0 0 8 0 0 % D
% Glu: 0 8 0 0 0 0 0 15 0 0 72 8 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 29 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 22 8 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 50 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 43 79 0 0 8 8 8 15 15 15 8 8 36 22 % K
% Leu: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 15 0 0 29 0 43 0 22 0 0 0 % P
% Gln: 0 0 0 8 0 0 43 0 8 15 8 36 58 0 0 % Q
% Arg: 0 22 0 0 0 0 8 0 8 0 0 15 15 15 50 % R
% Ser: 0 0 8 0 0 29 8 22 15 8 0 8 0 0 15 % S
% Thr: 15 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % T
% Val: 8 0 0 29 8 8 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 8 8 8 0 8 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _