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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SURF6 All Species: 8.79
Human Site: S248 Identified Species: 14.87
UniProt: O75683 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75683 NP_006744.2 361 41450 S248 E R L Q A R Q S R L D E L R G
Chimpanzee Pan troglodytes XP_001169391 361 41388 S248 E R L Q A R Q S R L D E L R G
Rhesus Macaque Macaca mulatta XP_001101299 361 41311 S248 E R L Q A R Q S R L D E L R D
Dog Lupus familis XP_849838 514 57534 A401 E R L Q A R Q A Q L D E L R D
Cat Felis silvestris
Mouse Mus musculus P70279 355 41216 G242 D R L Q A R Q G R L D E L R D
Rat Rattus norvegicus NP_001015014 354 40813 G241 D R L H A R Q G R V E E L R D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514709 169 20180 R128 Q V V E K M Q R R Q D R R R G
Chicken Gallus gallus NP_001025853 356 41570 N244 S R L E I R K N K L E E L K E
Frog Xenopus laevis Q9I8B0 341 39883 C228 S R L E A R K C K L E E L R A
Zebra Danio Brachydanio rerio NP_957359 362 41602 A250 T R I E A R K A H L E Q L R E
Tiger Blowfish Takifugu rubipres O57594 359 41402 A247 S R V E A R N A K L E G L R E
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q23525 472 54243 A369 A K V E E T K A T I A K V R E
Sea Urchin Strong. purpuratus XP_780432 428 48512 Q322 K K A E L K E Q K M A E M K E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36080 434 50463 N309 K L L E A K K N K M E A K D E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.4 48 N.A. 72.5 73.1 N.A. 34.3 49.3 49.8 44.4 45.4 N.A. N.A. 21.1 25.2
Protein Similarity: 100 99.4 97.7 58.3 N.A. 82.2 83.6 N.A. 42.6 70 68.9 67.6 67 N.A. N.A. 38.9 51.6
P-Site Identity: 100 100 93.3 80 N.A. 80 60 N.A. 33.3 40 53.3 40 40 N.A. N.A. 6.6 6.6
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 80 N.A. 53.3 80 80 80 73.3 N.A. N.A. 60 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 72 0 0 29 0 0 15 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 15 0 0 0 0 0 0 0 0 0 43 0 0 8 29 % D
% Glu: 29 0 0 58 8 0 8 0 0 0 43 65 0 0 43 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 15 0 0 0 8 0 0 22 % G
% His: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 8 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 15 15 0 0 8 15 36 0 36 0 0 8 8 15 0 % K
% Leu: 0 8 65 0 8 0 0 0 0 65 0 0 72 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 15 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 8 15 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 36 0 0 50 8 8 8 0 8 0 0 0 % Q
% Arg: 0 72 0 0 0 72 0 8 43 0 0 8 8 79 0 % R
% Ser: 22 0 0 0 0 0 0 22 0 0 0 0 0 0 0 % S
% Thr: 8 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % T
% Val: 0 8 22 0 0 0 0 0 0 8 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _