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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SURF6 All Species: 16.06
Human Site: S74 Identified Species: 27.18
UniProt: O75683 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75683 NP_006744.2 361 41450 S74 A K S L G E K S P A A S G A R
Chimpanzee Pan troglodytes XP_001169391 361 41388 S74 A K S L G E K S P A A S G A R
Rhesus Macaque Macaca mulatta XP_001101299 361 41311 S74 A K S L G E K S P A A S G A R
Dog Lupus familis XP_849838 514 57534 K233 P K S Q A L E K S P P A S R A
Cat Felis silvestris
Mouse Mus musculus P70279 355 41216 P74 T K A L G K K P P T S S R P K
Rat Rattus norvegicus NP_001015014 354 40813 S74 T K P L G K K S P T S S S A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514709 169 20180
Chicken Gallus gallus NP_001025853 356 41570 A81 K L A P G Q K A A P Q A N E S
Frog Xenopus laevis Q9I8B0 341 39883 Q71 K R T W N V P Q I T S N P Q K
Zebra Danio Brachydanio rerio NP_957359 362 41602 V71 N A N K N K P V V K G T P A T
Tiger Blowfish Takifugu rubipres O57594 359 41402 T77 S L S S I Q P T Q K G A A N K
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q23525 472 54243 P174 D S E D G E E P E G N N G A V
Sea Urchin Strong. purpuratus XP_780432 428 48512 S115 R E K S E D E S E S D A V G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36080 434 50463 K87 P V V L P G E K F K H M K M Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.4 48 N.A. 72.5 73.1 N.A. 34.3 49.3 49.8 44.4 45.4 N.A. N.A. 21.1 25.2
Protein Similarity: 100 99.4 97.7 58.3 N.A. 82.2 83.6 N.A. 42.6 70 68.9 67.6 67 N.A. N.A. 38.9 51.6
P-Site Identity: 100 100 100 13.3 N.A. 40 53.3 N.A. 0 13.3 0 6.6 6.6 N.A. N.A. 26.6 6.6
P-Site Similarity: 100 100 100 26.6 N.A. 66.6 73.3 N.A. 0 40 33.3 26.6 40 N.A. N.A. 40 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 8 15 0 8 0 0 8 8 22 22 29 8 43 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 8 0 8 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 8 8 0 8 29 29 0 15 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 50 8 0 0 0 8 15 0 29 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 15 43 8 8 0 22 43 15 0 22 0 0 8 0 29 % K
% Leu: 0 15 0 43 0 8 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % M
% Asn: 8 0 8 0 15 0 0 0 0 0 8 15 8 8 0 % N
% Pro: 15 0 8 8 8 0 22 15 36 15 8 0 15 8 0 % P
% Gln: 0 0 0 8 0 15 0 8 8 0 8 0 0 8 8 % Q
% Arg: 8 8 0 0 0 0 0 0 0 0 0 0 8 8 22 % R
% Ser: 8 8 36 15 0 0 0 36 8 8 22 36 15 0 8 % S
% Thr: 15 0 8 0 0 0 0 8 0 22 0 8 0 0 15 % T
% Val: 0 8 8 0 0 8 0 8 8 0 0 0 8 0 8 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _