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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1B
All Species:
10.61
Human Site:
S265
Identified Species:
19.44
UniProt:
O75688
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75688
NP_002697.1
479
52643
S265
V
K
S
R
L
E
V
S
D
D
L
E
N
V
C
Chimpanzee
Pan troglodytes
XP_001167412
430
48336
M231
Q
N
A
G
G
S
V
M
I
Q
R
V
N
G
S
Rhesus Macaque
Macaca mulatta
XP_001111662
479
52622
S265
V
K
S
R
L
E
V
S
D
D
L
E
N
V
C
Dog
Lupus familis
XP_851683
479
52774
S265
V
K
S
R
L
E
V
S
D
D
L
E
N
V
C
Cat
Felis silvestris
Mouse
Mus musculus
P36993
390
42776
R191
G
G
S
V
M
I
Q
R
V
N
G
S
L
A
V
Rat
Rattus norvegicus
P35815
390
42871
R191
G
G
S
V
M
I
Q
R
V
N
G
S
L
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512797
382
42443
M183
Q
N
A
G
G
S
V
M
I
Q
R
V
N
G
S
Chicken
Gallus gallus
NP_001026223
387
42716
M188
Q
N
A
G
G
S
V
M
I
Q
R
V
N
G
S
Frog
Xenopus laevis
NP_001085063
455
50420
E252
I
W
D
V
M
S
N
E
E
L
C
E
F
V
K
Zebra Danio
Brachydanio rerio
NP_001007314
382
42180
M182
Q
N
A
G
G
S
V
M
I
Q
R
V
N
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49596
356
39046
S157
L
S
F
D
H
K
P
S
H
E
T
E
A
R
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81716
355
39336
G156
G
P
H
S
D
F
T
G
P
T
S
G
C
T
A
Baker's Yeast
Sacchar. cerevisiae
P34221
468
51372
G256
V
H
Y
G
I
S
Q
G
N
M
T
L
S
D
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.6
99.5
97.2
N.A.
76.1
77
N.A.
62
77.2
78.9
67.6
N.A.
N.A.
N.A.
31.3
N.A.
Protein Similarity:
100
71.4
100
99.1
N.A.
79.9
79.3
N.A.
70.9
79.1
86.4
74.7
N.A.
N.A.
N.A.
46.9
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
6.6
6.6
N.A.
13.3
13.3
13.3
13.3
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
20
100
100
N.A.
20
20
N.A.
20
20
33.3
20
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
29.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.6
48
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
31
0
0
0
0
0
0
0
0
0
8
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
24
% C
% Asp:
0
0
8
8
8
0
0
0
24
24
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
24
0
8
8
8
0
39
0
0
0
% E
% Phe:
0
0
8
0
0
8
0
0
0
0
0
0
8
0
0
% F
% Gly:
24
16
0
39
31
0
0
16
0
0
16
8
0
31
0
% G
% His:
0
8
8
0
8
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
16
0
0
31
0
0
0
0
0
8
% I
% Lys:
0
24
0
0
0
8
0
0
0
0
0
0
0
0
8
% K
% Leu:
8
0
0
0
24
0
0
0
0
8
24
8
16
0
0
% L
% Met:
0
0
0
0
24
0
0
31
0
8
0
0
0
0
0
% M
% Asn:
0
31
0
0
0
0
8
0
8
16
0
0
54
0
0
% N
% Pro:
0
8
0
0
0
0
8
0
8
0
0
0
0
0
0
% P
% Gln:
31
0
0
0
0
0
24
0
0
31
0
0
0
0
0
% Q
% Arg:
0
0
0
24
0
0
0
16
0
0
31
0
0
8
8
% R
% Ser:
0
8
39
8
0
47
0
31
0
0
8
16
8
0
31
% S
% Thr:
0
0
0
0
0
0
8
0
0
8
16
0
0
8
0
% T
% Val:
31
0
0
24
0
0
54
0
16
0
0
31
0
31
16
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _