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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1B
All Species:
9.39
Human Site:
S428
Identified Species:
17.22
UniProt:
O75688
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75688
NP_002697.1
479
52643
S428
A
K
V
E
G
E
E
S
P
A
E
P
A
A
T
Chimpanzee
Pan troglodytes
XP_001167412
430
48336
H380
E
G
V
P
D
L
V
H
V
M
R
T
L
A
S
Rhesus Macaque
Macaca mulatta
XP_001111662
479
52622
S428
A
K
V
E
G
E
E
S
P
A
E
P
A
A
T
Dog
Lupus familis
XP_851683
479
52774
S428
A
K
V
E
G
E
E
S
P
A
E
P
A
A
T
Cat
Felis silvestris
Mouse
Mus musculus
P36993
390
42776
R340
P
D
L
A
H
V
M
R
I
L
S
A
E
N
I
Rat
Rattus norvegicus
P35815
390
42871
R340
P
D
L
A
H
V
M
R
I
L
S
A
E
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512797
382
42443
H332
E
G
V
P
D
L
V
H
V
M
R
T
L
A
T
Chicken
Gallus gallus
NP_001026223
387
42716
H337
E
G
M
P
D
L
A
H
V
I
R
I
L
S
A
Frog
Xenopus laevis
NP_001085063
455
50420
R404
R
E
L
R
I
N
H
R
G
N
Y
R
Q
L
L
Zebra Danio
Brachydanio rerio
NP_001007314
382
42180
H332
E
G
I
P
D
L
S
H
I
M
H
N
L
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49596
356
39046
T306
C
A
R
P
A
V
F
T
G
V
N
N
E
D
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81716
355
39336
V305
S
T
V
C
E
K
V
V
D
R
C
L
A
P
D
Baker's Yeast
Sacchar. cerevisiae
P34221
468
51372
G418
G
N
T
S
Y
F
H
G
A
S
L
S
D
M
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.6
99.5
97.2
N.A.
76.1
77
N.A.
62
77.2
78.9
67.6
N.A.
N.A.
N.A.
31.3
N.A.
Protein Similarity:
100
71.4
100
99.1
N.A.
79.9
79.3
N.A.
70.9
79.1
86.4
74.7
N.A.
N.A.
N.A.
46.9
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
0
0
N.A.
20
0
0
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
20
100
100
N.A.
6.6
6.6
N.A.
20
13.3
13.3
6.6
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
29.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.6
48
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
8
0
16
8
0
8
0
8
24
0
16
31
39
8
% A
% Cys:
8
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
16
0
0
31
0
0
0
8
0
0
0
8
8
8
% D
% Glu:
31
8
0
24
8
24
24
0
0
0
24
0
24
0
0
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
31
0
0
24
0
0
8
16
0
0
0
0
0
8
% G
% His:
0
0
0
0
16
0
16
31
0
0
8
0
0
8
0
% H
% Ile:
0
0
8
0
8
0
0
0
24
8
0
8
0
0
16
% I
% Lys:
0
24
0
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
24
0
0
31
0
0
0
16
8
8
31
8
16
% L
% Met:
0
0
8
0
0
0
16
0
0
24
0
0
0
8
0
% M
% Asn:
0
8
0
0
0
8
0
0
0
8
8
16
0
16
0
% N
% Pro:
16
0
0
39
0
0
0
0
24
0
0
24
0
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
8
0
8
8
0
0
0
24
0
8
24
8
0
0
0
% R
% Ser:
8
0
0
8
0
0
8
24
0
8
16
8
0
8
8
% S
% Thr:
0
8
8
0
0
0
0
8
0
0
0
16
0
0
31
% T
% Val:
0
0
47
0
0
24
24
8
24
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _