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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPM1B All Species: 13.64
Human Site: T10 Identified Species: 25
UniProt: O75688 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75688 NP_002697.1 479 52643 T10 A F L D K P K T E K H N A H G
Chimpanzee Pan troglodytes XP_001167412 430 48336
Rhesus Macaque Macaca mulatta XP_001111662 479 52622 T10 A F L D K P K T E K H N A H G
Dog Lupus familis XP_851683 479 52774 T10 A F L D K P K T E K H N A H G
Cat Felis silvestris
Mouse Mus musculus P36993 390 42776
Rat Rattus norvegicus P35815 390 42871
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512797 382 42443
Chicken Gallus gallus NP_001026223 387 42716
Frog Xenopus laevis NP_001085063 455 50420 T10 A F L D K P K T E K H N A H G
Zebra Danio Brachydanio rerio NP_001007314 382 42180
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P49596 356 39046
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81716 355 39336
Baker's Yeast Sacchar. cerevisiae P34221 468 51372 K12 L S N P I I D K E H H S G T D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.6 99.5 97.2 N.A. 76.1 77 N.A. 62 77.2 78.9 67.6 N.A. N.A. N.A. 31.3 N.A.
Protein Similarity: 100 71.4 100 99.1 N.A. 79.9 79.3 N.A. 70.9 79.1 86.4 74.7 N.A. N.A. N.A. 46.9 N.A.
P-Site Identity: 100 0 100 100 N.A. 0 0 N.A. 0 0 100 0 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 0 100 100 N.A. 0 0 N.A. 0 0 100 0 N.A. N.A. N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.3 29.8 N.A.
Protein Similarity: N.A. N.A. N.A. 38.6 48 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 31 0 0 0 0 0 0 0 0 0 0 0 31 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 31 0 0 8 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 39 0 0 0 0 0 0 % E
% Phe: 0 31 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 31 % G
% His: 0 0 0 0 0 0 0 0 0 8 39 0 0 31 0 % H
% Ile: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 31 0 31 8 0 31 0 0 0 0 0 % K
% Leu: 8 0 31 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 31 0 0 0 % N
% Pro: 0 0 0 8 0 31 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 31 0 0 0 0 0 8 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _