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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1B
All Species:
11.21
Human Site:
T435
Identified Species:
20.56
UniProt:
O75688
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75688
NP_002697.1
479
52643
T435
S
P
A
E
P
A
A
T
A
T
S
S
N
S
D
Chimpanzee
Pan troglodytes
XP_001167412
430
48336
S387
H
V
M
R
T
L
A
S
E
N
I
P
S
L
P
Rhesus Macaque
Macaca mulatta
XP_001111662
479
52622
T435
S
P
A
E
P
A
A
T
A
T
S
S
N
S
D
Dog
Lupus familis
XP_851683
479
52774
T435
S
P
A
E
P
A
A
T
A
T
S
S
N
S
D
Cat
Felis silvestris
Mouse
Mus musculus
P36993
390
42776
I347
R
I
L
S
A
E
N
I
P
N
L
P
P
G
G
Rat
Rattus norvegicus
P35815
390
42871
I347
R
I
L
S
A
E
N
I
P
N
L
P
P
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512797
382
42443
T339
H
V
M
R
T
L
A
T
E
S
I
P
N
L
P
Chicken
Gallus gallus
NP_001026223
387
42716
A344
H
V
I
R
I
L
S
A
E
N
I
P
N
L
P
Frog
Xenopus laevis
NP_001085063
455
50420
L411
R
G
N
Y
R
Q
L
L
E
E
M
L
C
S
Y
Zebra Danio
Brachydanio rerio
NP_001007314
382
42180
P339
H
I
M
H
N
L
H
P
E
T
I
P
N
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49596
356
39046
G313
T
G
V
N
N
E
D
G
D
Q
N
Q
I
Q
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81716
355
39336
D312
V
D
R
C
L
A
P
D
T
A
T
G
E
G
C
Baker's Yeast
Sacchar. cerevisiae
P34221
468
51372
L425
G
A
S
L
S
D
M
L
A
S
L
S
N
A
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.6
99.5
97.2
N.A.
76.1
77
N.A.
62
77.2
78.9
67.6
N.A.
N.A.
N.A.
31.3
N.A.
Protein Similarity:
100
71.4
100
99.1
N.A.
79.9
79.3
N.A.
70.9
79.1
86.4
74.7
N.A.
N.A.
N.A.
46.9
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
0
0
N.A.
20
6.6
6.6
13.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
20
100
100
N.A.
0
0
N.A.
26.6
13.3
6.6
13.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
29.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.6
48
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
24
0
16
31
39
8
31
8
0
0
0
8
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
8
% C
% Asp:
0
8
0
0
0
8
8
8
8
0
0
0
0
0
24
% D
% Glu:
0
0
0
24
0
24
0
0
39
8
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
16
0
0
0
0
0
8
0
0
0
8
0
24
16
% G
% His:
31
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
24
8
0
8
0
0
16
0
0
31
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
16
8
8
31
8
16
0
0
24
8
0
31
0
% L
% Met:
0
0
24
0
0
0
8
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
8
16
0
16
0
0
31
8
0
54
0
0
% N
% Pro:
0
24
0
0
24
0
8
8
16
0
0
47
16
0
31
% P
% Gln:
0
0
0
0
0
8
0
0
0
8
0
8
0
8
8
% Q
% Arg:
24
0
8
24
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
24
0
8
16
8
0
8
8
0
16
24
31
8
31
0
% S
% Thr:
8
0
0
0
16
0
0
31
8
31
8
0
0
0
0
% T
% Val:
8
24
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _