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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1B
All Species:
13.64
Human Site:
Y59
Identified Species:
25
UniProt:
O75688
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75688
NP_002697.1
479
52643
Y59
D
W
S
F
F
A
V
Y
D
G
H
A
G
S
R
Chimpanzee
Pan troglodytes
XP_001167412
430
48336
K38
K
R
M
C
E
R
K
K
Y
E
T
D
L
E
D
Rhesus Macaque
Macaca mulatta
XP_001111662
479
52622
Y59
D
W
S
F
F
A
V
Y
D
G
H
A
G
S
R
Dog
Lupus familis
XP_851683
479
52774
Y59
D
W
S
F
F
A
V
Y
D
G
H
A
G
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P36993
390
42776
Rat
Rattus norvegicus
P35815
390
42871
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512797
382
42443
Chicken
Gallus gallus
NP_001026223
387
42716
Frog
Xenopus laevis
NP_001085063
455
50420
Y59
D
W
S
F
F
A
V
Y
D
G
H
A
G
S
R
Zebra Danio
Brachydanio rerio
NP_001007314
382
42180
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49596
356
39046
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81716
355
39336
Baker's Yeast
Sacchar. cerevisiae
P34221
468
51372
F61
H
L
A
F
Y
G
I
F
D
G
H
G
G
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.6
99.5
97.2
N.A.
76.1
77
N.A.
62
77.2
78.9
67.6
N.A.
N.A.
N.A.
31.3
N.A.
Protein Similarity:
100
71.4
100
99.1
N.A.
79.9
79.3
N.A.
70.9
79.1
86.4
74.7
N.A.
N.A.
N.A.
46.9
N.A.
P-Site Identity:
100
0
100
100
N.A.
0
0
N.A.
0
0
100
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
0
100
100
N.A.
0
0
N.A.
0
0
100
0
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
29.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.6
48
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
31
0
0
0
0
0
31
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
31
0
0
0
0
0
0
0
39
0
0
8
0
0
8
% D
% Glu:
0
0
0
0
8
0
0
0
0
8
0
0
0
8
0
% E
% Phe:
0
0
0
39
31
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
39
0
8
39
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
39
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
31
% R
% Ser:
0
0
31
0
0
0
0
0
0
0
0
0
0
39
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
31
0
0
0
0
0
0
0
0
% V
% Trp:
0
31
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
31
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _