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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAP1
All Species:
34.85
Human Site:
Y113
Identified Species:
63.89
UniProt:
O75689
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75689
NP_006860.1
374
43395
Y113
E
Q
W
I
R
A
K
Y
E
R
Q
E
F
I
Y
Chimpanzee
Pan troglodytes
XP_001174772
381
44399
Y117
E
Q
W
I
R
A
K
Y
E
R
R
E
F
M
A
Rhesus Macaque
Macaca mulatta
XP_001084174
374
43391
Y113
E
Q
W
I
R
A
K
Y
E
R
Q
E
F
I
Y
Dog
Lupus familis
XP_848516
374
43415
Y113
E
Q
W
I
R
A
K
Y
E
R
Q
E
F
T
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2V5
381
43971
Y117
E
Q
W
I
R
A
K
Y
E
R
Q
E
F
T
A
Rat
Rattus norvegicus
Q9JK15
376
43505
Y117
E
Q
W
I
R
A
K
Y
E
R
Q
E
F
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F413
428
46296
K121
I
R
D
K
Y
E
K
K
K
Y
M
D
R
S
I
Frog
Xenopus laevis
NP_001087001
375
43591
Y114
E
Q
W
I
R
A
K
Y
E
R
K
E
F
I
L
Zebra Danio
Brachydanio rerio
NP_001002715
377
43462
Y115
E
Q
W
I
R
A
K
Y
E
R
Q
E
F
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624178
375
43097
Y114
E
Q
W
I
R
A
K
Y
E
R
E
E
F
C
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783514
333
39292
G88
V
A
F
M
E
A
H
G
N
L
K
A
K
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FVJ3
337
37127
S94
G
G
N
A
S
A
N
S
I
Y
E
A
F
I
P
Baker's Yeast
Sacchar. cerevisiae
P40529
298
32620
L66
S
K
V
K
S
V
D
L
D
T
W
K
E
E
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.9
98.9
93.3
N.A.
57.2
58.5
N.A.
N.A.
21.2
79.1
61.5
N.A.
N.A.
46.1
N.A.
40.3
Protein Similarity:
100
73.4
99.7
96.2
N.A.
73.2
75.2
N.A.
N.A.
36.4
90.6
79.5
N.A.
N.A.
69.5
N.A.
60.7
P-Site Identity:
100
80
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
6.6
86.6
86.6
N.A.
N.A.
80
N.A.
6.6
P-Site Similarity:
100
93.3
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
26.6
93.3
86.6
N.A.
N.A.
93.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.1
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.7
40.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
85
0
0
0
0
0
16
0
0
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
0
0
0
8
0
8
0
0
8
0
0
0
% D
% Glu:
70
0
0
0
8
8
0
0
70
0
16
70
8
16
8
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
77
0
0
% F
% Gly:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
24
% H
% Ile:
8
0
0
70
0
0
0
0
8
0
0
0
0
31
8
% I
% Lys:
0
8
0
16
0
0
77
8
8
0
16
8
8
0
8
% K
% Leu:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
8
0
0
16
0
% M
% Asn:
0
0
8
0
0
0
8
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
70
0
0
0
0
0
0
0
0
47
0
0
0
0
% Q
% Arg:
0
8
0
0
70
0
0
0
0
70
8
0
8
0
0
% R
% Ser:
8
0
0
0
16
0
0
8
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
0
0
24
0
% T
% Val:
8
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
70
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
70
0
16
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _