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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAP1
All Species:
28.48
Human Site:
Y232
Identified Species:
52.22
UniProt:
O75689
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75689
NP_006860.1
374
43395
Y232
L
R
A
A
R
F
H
Y
L
Q
V
A
F
P
G
Chimpanzee
Pan troglodytes
XP_001174772
381
44399
Y235
L
R
A
A
R
L
Q
Y
L
K
M
A
F
P
E
Rhesus Macaque
Macaca mulatta
XP_001084174
374
43391
Y232
L
R
A
A
R
F
H
Y
L
Q
V
A
F
P
G
Dog
Lupus familis
XP_848516
374
43415
Y232
L
R
A
A
R
F
H
Y
L
Q
V
A
F
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2V5
381
43971
Y235
L
R
A
A
R
L
Q
Y
L
K
L
A
F
P
D
Rat
Rattus norvegicus
Q9JK15
376
43505
Y234
L
R
A
A
R
L
Q
Y
L
K
L
A
F
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F413
428
46296
G233
S
G
S
M
P
T
S
G
S
A
G
S
V
P
E
Frog
Xenopus laevis
NP_001087001
375
43591
Y233
I
R
A
A
R
F
H
Y
L
Q
V
A
Y
P
R
Zebra Danio
Brachydanio rerio
NP_001002715
377
43462
Y234
I
R
A
A
Q
L
H
Y
L
K
V
A
F
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624178
375
43097
R232
I
R
C
A
K
L
H
R
L
Q
V
A
Y
P
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783514
333
39292
R193
I
R
H
A
K
F
N
R
L
K
V
A
Y
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FVJ3
337
37127
V206
M
S
S
D
P
Y
V
V
L
T
L
G
Q
Q
K
Baker's Yeast
Sacchar. cerevisiae
P40529
298
32620
P171
Q
K
T
Q
T
Q
P
P
S
H
L
L
S
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.9
98.9
93.3
N.A.
57.2
58.5
N.A.
N.A.
21.2
79.1
61.5
N.A.
N.A.
46.1
N.A.
40.3
Protein Similarity:
100
73.4
99.7
96.2
N.A.
73.2
75.2
N.A.
N.A.
36.4
90.6
79.5
N.A.
N.A.
69.5
N.A.
60.7
P-Site Identity:
100
66.6
100
100
N.A.
66.6
66.6
N.A.
N.A.
6.6
80
73.3
N.A.
N.A.
60
N.A.
53.3
P-Site Similarity:
100
80
100
100
N.A.
80
80
N.A.
N.A.
20
93.3
93.3
N.A.
N.A.
80
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.1
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.7
40.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
62
77
0
0
0
0
0
8
0
77
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
16
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% E
% Phe:
0
0
0
0
0
39
0
0
0
0
0
0
54
0
0
% F
% Gly:
0
8
0
0
0
0
0
8
0
0
8
8
0
0
47
% G
% His:
0
0
8
0
0
0
47
0
0
8
0
0
0
0
0
% H
% Ile:
31
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
16
0
0
0
0
39
0
0
0
0
8
% K
% Leu:
47
0
0
0
0
39
0
0
85
0
31
8
0
0
0
% L
% Met:
8
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
16
0
8
8
0
0
0
0
0
85
0
% P
% Gln:
8
0
0
8
8
8
24
0
0
39
0
0
8
8
0
% Q
% Arg:
0
77
0
0
54
0
0
16
0
0
0
0
0
0
8
% R
% Ser:
8
8
16
0
0
0
8
0
16
0
0
8
8
0
8
% S
% Thr:
0
0
8
0
8
8
0
0
0
8
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
8
8
0
0
54
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
62
0
0
0
0
24
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _