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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAP1
All Species:
19.09
Human Site:
Y306
Identified Species:
35
UniProt:
O75689
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75689
NP_006860.1
374
43395
Y306
I
G
S
K
E
S
G
Y
T
V
L
H
G
F
P
Chimpanzee
Pan troglodytes
XP_001174772
381
44399
Y311
L
G
N
K
E
Q
G
Y
E
A
Y
E
D
L
P
Rhesus Macaque
Macaca mulatta
XP_001084174
374
43391
Y306
I
G
S
K
E
S
G
Y
T
V
L
H
G
F
P
Dog
Lupus familis
XP_848516
374
43415
Y306
I
G
S
R
E
S
G
Y
T
V
L
D
G
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2V5
381
43971
Y311
L
G
S
N
E
Q
G
Y
E
V
W
E
D
L
P
Rat
Rattus norvegicus
Q9JK15
376
43505
Y310
L
G
S
N
E
Q
G
Y
E
V
W
E
G
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F413
428
46296
V346
V
G
N
V
Q
A
A
V
I
G
V
P
N
G
M
Frog
Xenopus laevis
NP_001087001
375
43591
Y307
I
G
S
A
E
N
N
Y
E
V
Q
E
G
L
P
Zebra Danio
Brachydanio rerio
NP_001002715
377
43462
R309
G
H
R
D
H
G
Y
R
V
T
I
G
L
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624178
375
43097
D304
I
F
L
G
H
S
S
D
G
F
A
V
K
T
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783514
333
39292
F267
L
G
T
R
S
D
G
F
T
V
R
E
G
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FVJ3
337
37127
G276
I
T
S
A
M
A
F
G
D
P
E
M
F
G
D
Baker's Yeast
Sacchar. cerevisiae
P40529
298
32620
S240
L
S
L
Y
S
K
P
S
A
Q
T
Q
S
Q
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.9
98.9
93.3
N.A.
57.2
58.5
N.A.
N.A.
21.2
79.1
61.5
N.A.
N.A.
46.1
N.A.
40.3
Protein Similarity:
100
73.4
99.7
96.2
N.A.
73.2
75.2
N.A.
N.A.
36.4
90.6
79.5
N.A.
N.A.
69.5
N.A.
60.7
P-Site Identity:
100
40
100
80
N.A.
46.6
53.3
N.A.
N.A.
6.6
53.3
0
N.A.
N.A.
13.3
N.A.
40
P-Site Similarity:
100
53.3
100
86.6
N.A.
53.3
60
N.A.
N.A.
40
60
6.6
N.A.
N.A.
13.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.1
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.7
40.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
16
8
0
8
8
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
0
8
8
0
0
8
16
0
8
% D
% Glu:
0
0
0
0
54
0
0
0
31
0
8
39
0
0
0
% E
% Phe:
0
8
0
0
0
0
8
8
0
8
0
0
8
16
0
% F
% Gly:
8
70
0
8
0
8
54
8
8
8
0
8
47
16
8
% G
% His:
0
8
0
0
16
0
0
0
0
0
0
16
0
0
0
% H
% Ile:
47
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% I
% Lys:
0
0
0
24
0
8
0
0
0
0
0
0
8
0
0
% K
% Leu:
39
0
16
0
0
0
0
0
0
0
24
0
8
39
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
8
% M
% Asn:
0
0
16
16
0
8
8
0
0
0
0
0
8
0
8
% N
% Pro:
0
0
0
0
0
0
8
0
0
8
0
8
0
8
62
% P
% Gln:
0
0
0
0
8
24
0
0
0
8
8
8
0
8
0
% Q
% Arg:
0
0
8
16
0
0
0
8
0
0
8
0
0
0
0
% R
% Ser:
0
8
54
0
16
31
8
8
0
0
0
0
8
0
0
% S
% Thr:
0
8
8
0
0
0
0
0
31
8
8
0
0
8
0
% T
% Val:
8
0
0
8
0
0
0
8
8
54
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
8
54
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _