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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUP155
All Species:
22.12
Human Site:
T185
Identified Species:
40.56
UniProt:
O75694
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75694
NP_004289.1
1391
155199
T185
L
S
Y
A
N
L
Q
T
G
S
G
V
L
N
D
Chimpanzee
Pan troglodytes
XP_517798
1391
155258
T185
L
S
Y
A
N
L
Q
T
G
S
G
V
L
N
D
Rhesus Macaque
Macaca mulatta
XP_001094346
1394
156555
T184
L
S
Y
A
N
L
Q
T
G
S
G
V
L
N
D
Dog
Lupus familis
XP_536500
1378
153857
L183
L
G
L
S
Y
A
N
L
Q
T
G
I
G
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q99P88
1391
155099
T185
L
S
Y
A
N
V
Q
T
G
S
G
I
L
N
D
Rat
Rattus norvegicus
P37199
1390
154984
T184
L
S
Y
A
N
V
Q
T
G
S
G
I
L
N
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509326
1323
147640
T163
L
S
Y
T
N
L
Q
T
G
C
G
V
L
N
D
Chicken
Gallus gallus
XP_425016
1386
153891
A178
L
S
C
A
N
T
Q
A
G
T
G
P
L
N
D
Frog
Xenopus laevis
NP_001080800
1388
154744
L179
L
G
L
S
F
A
N
L
Q
P
G
N
L
N
D
Zebra Danio
Brachydanio rerio
NP_956450
1391
155007
K177
I
L
G
L
S
F
P
K
V
Q
T
G
L
N
D
Tiger Blowfish
Takifugu rubipres
NP_001027921
1370
152645
K177
I
L
G
L
S
F
P
K
G
Q
A
G
L
N
D
Fruit Fly
Dros. melanogaster
NP_477287
1365
153877
I163
L
T
T
P
I
E
V
I
V
L
G
V
T
F
G
Honey Bee
Apis mellifera
XP_396174
1268
142379
K148
S
V
G
L
V
K
P
K
P
N
V
F
Q
S
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
93.4
95
N.A.
94.9
93.7
N.A.
85.4
85.3
79
73.5
72.2
32
36
N.A.
N.A.
Protein Similarity:
100
99.7
94.9
96.8
N.A.
97.6
96.5
N.A.
90.5
92.1
88.7
86.3
85.1
52.1
57.3
N.A.
N.A.
P-Site Identity:
100
100
100
20
N.A.
86.6
86.6
N.A.
86.6
66.6
33.3
20
26.6
20
0
N.A.
N.A.
P-Site Similarity:
100
100
100
40
N.A.
100
100
N.A.
86.6
73.3
40
33.3
40
26.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
47
0
16
0
8
0
0
8
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
77
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
16
0
0
0
0
0
8
0
8
0
% F
% Gly:
0
16
24
0
0
0
0
0
62
0
77
16
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
8
0
0
8
0
0
0
24
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
24
0
0
0
0
0
0
0
% K
% Leu:
77
16
16
24
0
31
0
16
0
8
0
0
77
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
54
0
16
0
0
8
0
8
0
85
0
% N
% Pro:
0
0
0
8
0
0
24
0
8
8
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
54
0
16
16
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
54
0
16
16
0
0
0
0
39
0
0
0
8
0
% S
% Thr:
0
8
8
8
0
8
0
47
0
16
8
0
8
0
0
% T
% Val:
0
8
0
0
8
16
8
0
16
0
8
39
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
47
0
8
0
0
0
0
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _