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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RP2 All Species: 28.79
Human Site: S219 Identified Species: 63.33
UniProt: O75695 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75695 NP_008846.2 350 39641 S219 V S T E A N R S I V P I S R G
Chimpanzee Pan troglodytes XP_521029 333 37760 S219 V S T E A N R S I V P I S R G
Rhesus Macaque Macaca mulatta XP_001099993 294 33622 L207 P I P T T E E L K A V R V S T
Dog Lupus familis XP_548972 350 39342 S219 V S T E A N R S I V P V S R G
Cat Felis silvestris
Mouse Mus musculus Q9EPK2 347 39358 S216 I S T E A N R S I V P V S R G
Rat Rattus norvegicus NP_001102482 350 39637 S219 I S T D P N R S I V P V S R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZHN4 357 39704 S226 V S T D A M K S I I P I T R G
Frog Xenopus laevis Q8AVX5 353 39948 S222 V S A D V H K S I I P V T W G
Zebra Danio Brachydanio rerio NP_998611 311 34677 R212 D Y T T A N A R K L I D E A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_500127 341 38164 F229 L K P S P A D F I P R F T D T
Sea Urchin Strong. purpuratus XP_797121 345 38815 S214 A S L D P E K S V V P L T H G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.1 83.4 95.1 N.A. 88 88.5 N.A. N.A. 79.2 72.8 63.4 N.A. N.A. N.A. 28.8 46.5
Protein Similarity: 100 93.4 84 97.7 N.A. 93.1 93.4 N.A. N.A. 89 88.3 74.8 N.A. N.A. N.A. 46.5 66.8
P-Site Identity: 100 100 0 93.3 N.A. 86.6 73.3 N.A. N.A. 66.6 40 20 N.A. N.A. N.A. 6.6 33.3
P-Site Similarity: 100 100 0 100 N.A. 100 93.3 N.A. N.A. 93.3 80 26.6 N.A. N.A. N.A. 20 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 55 10 10 0 0 10 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 37 0 0 10 0 0 0 0 10 0 10 0 % D
% Glu: 0 0 0 37 0 19 10 0 0 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % H
% Ile: 19 10 0 0 0 0 0 0 73 19 10 28 0 0 0 % I
% Lys: 0 10 0 0 0 0 28 0 19 0 0 0 0 0 0 % K
% Leu: 10 0 10 0 0 0 0 10 0 10 0 10 0 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 55 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 19 0 28 0 0 0 0 10 73 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 46 10 0 0 10 10 0 55 0 % R
% Ser: 0 73 0 10 0 0 0 73 0 0 0 0 46 10 0 % S
% Thr: 0 0 64 19 10 0 0 0 0 0 0 0 37 0 28 % T
% Val: 46 0 0 0 10 0 0 0 10 55 10 37 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _